Selenocysteine Synthase
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. Identificação de elementos estruturais no tRNAsecuca determinantes da ligação com proteínas / Identification of structural elements of the tRNAsecuca determining its protein binding
Em Escherichia coli a formação e incorporação do aminoácido selenocisteína é um evento cotraducional dirigido pelo códon de terminação UGA e deve se a uma complexa via de biosíntese cujas principais proteínas envolvidas são: Selenocisteína sintase (SELA), Fator de elongação de selenocisteína (SELB), Selenofosfato sintetase (SELD), Seril-tRNA
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/01/2012
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2. Structural determination of Selenocysteine Synthase from Escherichia coli / Determinação estrutural da proteína Selenocisteína Sintase de Escherichia coli
A biossíntese do 21o. aminoácido, Selenocisteína (Sec - U), envolve uma complexa maquinaria enzimática composta, em eubactérias, pela Selenocisteína Sintase (SELA), Fator de Elongação de Selenocisteína (SELB), Selenofosfato Sintetase (SELD) e tRNA de Inserção Selenocisteína (tRNAsec). Em arqueobactérias e eucariotos existem ainda O fosforil tRNA
Publicado em: 2010
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3. Estudos moleculares das enzimas Fosfoseril-tRNA sintease de Trypanosoma brucei e Leishmania major e Seril-tRNA sintease de Trypanosoma brucei / Molecular studies the enzymes Fosfoseril-tRNA Kinase of the Trypanosoma brucei and Leishmania major and Seril-tRNA Sintetase of the Trypanosoma brucei
The translation process study is central role in the cellular metabolism and attracts the interest of several groups, in particular, the study of the 21º amino acid, the selenocystein. The selenocystein incorporation pathway was described in Escherichia coli and recently in eukaryotes. The first step of this pathway is initiated by Seryl-tRNA Synthetase tha
Publicado em: 2009
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4. Estudos moleculares das enzimas envolvidas na biossíntese de selenocisteína em Trypanosoma brucei e Leishmania major / Molecular studies of the enzymes involved in selenocysteine synthesis in Trypanosoma brucei and Leishmania major
One of the main biological forms of the selenium incorporation is the amino acid form named selenocysteine (Sec, U), which is incorporated co-translationally at the emerging new polypeptide in the specific positions at the UGA codon, that is usually recognized as stop codon. The incorporation of the selenocysteine in E.coli is already solved with the involve
Publicado em: 2008
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5. Estudos moleculares da Selenocisteína Sintase (SELA) de Escherichia coli.
The study of translation processes attracts the interest of a wide range of research groups due to its main role in general cellular metabolism. In particular, the investigation of new amino acid residues, such as selenocysteine and pyrrolysin, which result in an expansion of the genetic code from the traditional 20 residues to a total of 22 residues up to t
Publicado em: 2005
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6. The function of SECIS RNA in translational control of gene expression in Escherichia coli
The incorporation of selenocysteine into proteins is directed by specific UGA codons and mRNA secondary structures, designated SECIS elements. In bacteria, these elements are positioned within the reading frame of selenoprotein mRNAs immediately downstream of the triplet coding for selenocysteine, and they tether a complex of the selenocysteine-specific elon
Oxford University Press.
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7. Eukaryotic selenocysteine inserting tRNA species support selenoprotein synthesis in Escherichia coli.
Although the tRNA species directing selenocysteine insertion in prokaryotes differ greatly in their primary structure from that of their eukaryotic homologues they share very similar three-dimensional structures. To analyse whether this conservation of the overall shape of the molecules reflects a conservation of their functional interactions it was tested w