Selenoprotein
Mostrando 1-12 de 66 artigos, teses e dissertações.
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1. Irisin and troponin I expression in dialysis patients submitted to remote ischemic preconditioning: a pilot study
RESUMO Introdução: A terapia de substituição renal continua associada a altas taxas de hospitalização e baixa qualidade de vida. A morbimortalidade por todas as causas na terapia de substituição renal é superior a 20% ao ano, sendo 44 vezes maior quando a diabetes está presente e mais de 10 vezes a da população em geral. Independentemente do tra
J. Bras. Nefrol.. Publicado em: 02/12/2019
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2. The role of selenium in insulin resistance
ABSTRACT In recent years, there has been growing interest in clarifying the pathogenesis of some chronic diseases, such as obesity and type 2 diabetes mellitus. Metabolic alterations in these diseases are characterized by chronic hyperglycemia and insulin resistance. Studies have demonstrated the participation of minerals in the pathogenesis of insulin resis
Braz. J. Pharm. Sci.. Publicado em: 14/05/2018
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3. Serum selenium and selenoprotein-P levels in autoimmune thyroid diseases patients in a select center: a transversal study
ABSTRACT Objective: Selenium (Se) supplementation has been used to help prevent the progression of Graves’ ophthalmopathy (GO) and autoimmune thyroid diseases (AITD) patients. We investigated Se serum and selenoprotein P (SePP) levels in Graves’ disease (GD) with and without GO, Hashimoto's thyroiditis (HT) patients and in 27 control individuals (C). S
Arch. Endocrinol. Metab.. Publicado em: 2017-12
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4. Validação da via de biossíntese de selenocisteína e selenoproteínas em Trypanosoma por RNA de interferência
Selênio (Se) é um elemento essencial encontrado em selenoproteínas na forma do 21 aminoácido selenocisteína (Sec U). A incorporação co-traducional de Sec depende de uma complexa via de síntese, de um códon de terminação UGA em fase de leitura e uma estrutura terciária do RNA mensageiro conhecida como elemento SECIS. A maioria das selenoproteínas
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/04/2012
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5. Isolation and characterization of genes functionally involved in ovarian development of the giant tiger shrimp Penaeus monodon by suppression subtractive hybridization (SSH)
Suppression subtractive hybridization (SSH) libraries between cDNA in stages I (previtellogenic) and III (cortical rod) ovaries of the giant tiger shrimp (Penaeus monodon) were established. In all, 452 ESTs were unidirectionally sequenced. Sequence assembly generated 28 contigs and 201 singletons, 109 of which (48.0%) corresponding to known sequences previou
Genetics and Molecular Biology. Publicado em: 2010
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6. EFFECT OF DIPHENYL DISELENIDE ON TOXICITY INDUCED BY MERCURIC CHLORIDE IN MICE / EFEITO DO DISSELENETO DE DIFENILA SOBRE A TOXICIDADE INDUZIDA POR CLORETO DE MERCÚRIO EM CAMUNDONGOS
Mercury is a metal without physiological functions in human body and is toxic to human beings. This metal has many applications in industry and, therefore it is very important in occupational and environmental exposure. The toxicity of mercury depends on the form of the metal and can affect several organs, such as brain, kidney and liver. In addition, mercur
Publicado em: 2008
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7. SECIS–SBP2 interactions dictate selenocysteine incorporation efficiency and selenoprotein hierarchy
Selenocysteine incorporation at UGA codons requires cis-acting mRNA secondary structures and several specialized trans-acting factors. The latter include a selenocysteine-specific tRNA, an elongation factor specific for this tRNA and a SECIS-binding protein, SBP2, which recruits the elongation factor to the selenoprotein mRNA. Overexpression of selenoprotein
Oxford University Press.
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8. Selenoprotein A of the clostridial glycine reductase complex: purification and amino acid sequence of the selenocysteine-containing peptide.
A selenium-containing protein, selenoprotein A, is an essential component of the clostridial glycine reductase complex. This enzyme complex catalyzes the reductive deamination of glycine, which is coupled to the esterification of orthophosphate resulting in the formation of ATP. Sequence information was obtained by automated Edman degradation of peptides gen
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9. Mammalian Selenoprotein in Which Selenocysteine (Sec) Incorporation Is Supported by a New Form of Sec Insertion Sequence Element
Selenocysteine (Sec), the 21st amino acid in protein, is encoded by UGA. The Sec insertion sequence (SECIS) element, which is the stem-loop structure present in 3" untranslated regions (UTRs) of eukaryotic selenoprotein-encoding genes, is essential for recognition of UGA as a codon for Sec rather than as a stop signal. We now report the identification of a n
American Society for Microbiology.
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10. A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity.
We report the isolation and characterization of a new selenoprotein from a human lung adenocarcinoma cell line, NCI-H441. Cells were grown in RPMI-1640 medium containing 10% (vol/vol) fetal bovine serum and 0.1 microM [75Se]selenite. A 75Se-labeled protein was isolated from sonic extracts of the cells by chromatography on DE-23, phenyl-Sepharose, heparin-aga
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11. Selenoproteins and selenocysteine insertion system in the model plant cell system, Chlamydomonas reinhardtii
Known eukaryotic selenocysteine (Sec)-containing proteins are animal proteins, whereas selenoproteins have not been found in yeast and plants. Surprisingly, we detected selenoproteins in a member of the plant kingdom, Chlamydomonas reinhardtii, and directly identified two of them as phospholipid hydroperoxide glutathione peroxidase and selenoprotein W homolo
Oxford University Press.
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12. Rat skeletal muscle selenoprotein W: cDNA clone and mRNA modulation by dietary selenium.
Rat skeletal muscle selenoprotein W cDNA was isolated and sequenced. The isolation strategy involved design of degenerate PCR primers from reverse translation of a partial peptide sequence. A reverse transcription-coupled PCR product from rat muscle mRNA was used to screen a muscle cDNA library prepared from selenium-supplemented rats. The cDNA sequence conf