Sequence Alignment Methods
Mostrando 1-12 de 117 artigos, teses e dissertações.
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1. Class III Malocclusion: Missense Mutations in DUSP6 Gene
Abstract Objective: To determine the DUSP6 gene mutation in three generations of Malaysian Malay subjects having Class III malocclusion. Material and Methods: Genetic analyses of DUSP6 gene were carried out in 30 subjects by selecting three individuals representing three generations, respectively, from ten Malaysian Malay families having Class III malocclu
Pesqui. Bras. Odontopediatria Clín. Integr.. Publicado em: 10/10/2019
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2. Sequence analysis of the cDNA encoding for SpCTx: a lethal factor from scorpionfish venom ( Scorpaena plumieri )
Abstract Background: Lethal factors are multifunctional oligomeric proteins found in the venomous apparatus of Scorpaeniformes fish. These toxins elicit not only an array of biological responses in vitro but also cardiovascular disorders and strong hemolytic, nociceptive and edematogenic activities in vivo. This work describes the cloning and molecular iden
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 21/09/2018
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3. Biofilm production by clinical isolates of Pseudomonas aeruginosa and structural changes in LasR protein of isolates non biofilm-producing
ABSTRACT Introduction: Biofilm production is an important mechanism for the survival of Pseudomonas aeruginosa and its relationship with antimicrobial resistance represents a challenge for patient therapeutics. P. aeruginosa is an opportunistic pathogen frequently associated to nosocomial infections, especially in imunocompromised hosts. Objectives: Analyz
Braz J Infect Dis. Publicado em: 2018-03
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4. Improved reverse transcription-polymerase chain reaction assay for the detection of flaviviruses with semi-nested primers for discrimination between dengue virus serotypes and Zika virus
BACKGROUND The genus Flavivirus includes a variety of medically important viruses, including dengue virus (DENV) and Zika virus (ZIKV), which are most prevalent in Brazil. Because the clinical profile of patients affected by different DENV serotypes or ZIKV may be similar, the development of new methods that facilitate a rapid and accurate diagnosis is cru
Mem. Inst. Oswaldo Cruz. Publicado em: 26/02/2018
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5. Preparation of monoclonal antibodies against gamma-type phospholipase A2 inhibitors and immunodetection of these proteins in snake blood
Abstract Background: The gamma-type phospholipase A2 inhibitor (ΡLIγ) is a natural protein commonly found in snake serum, which can neutralize pathophysiological effects of snake venom phospholipases A2. Therefore, this protein is a potential candidate to the development of a novel antivenom. To the best of our knowledge, there is no antibody currently av
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 28/09/2017
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6. Comparisons Between Different Methods in Measuring Enzyme Similarity for Metabolic Network Alignment
Metabolic network alignments enable comparison of the similarities and differences between pathways in two metabolic networks and help to uncover the conserved sub-blocks therein. Such analysis is important in the understanding of metabolic networks and species evolution. The fundamental parts of metabolic network alignment algorithms all involve comparisons
Braz. arch. biol. technol.. Publicado em: 22/03/2016
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7. Molecular cloning of a hyaluronidase from Bothrops pauloensis venom gland
Background Hyaluronate is one of the major components of extracellular matrix from vertebrates whose breakdown is catalyzed by the enzyme hyaluronidase. These enzymes are widely described in snake venoms, in which they facilitate the spreading of the main toxins in the victim’s body during the envenoming. Snake venoms also present some variants (hyaluron
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 05/08/2014
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8. A primary assessment of the endophytic bacterial community in a xerophilous moss (Grimmia montana) using molecular method and cultivated isolates
Investigating the endophytic bacterial community in special moss species is fundamental to understanding the microbial-plant interactions and discovering the bacteria with stresses tolerance. Thus, the community structure of endophytic bacteria in the xerophilous moss Grimmia montana were estimated using a 16S rDNA library and traditional cultivation methods
Braz. J. Microbiol.. Publicado em: 2014
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9. Técnicas de bioinformática aplicadas ao estudo de poligalacturonases de fungos
Plant cell walls are composed of approximately 65% cellulose microfibrils and pectin. The latter is proteolytically degraded by the so-called pectinases enzymes (also known as pectinolytic enzymes). Pectinases may be either depolymerizing. They are produced by plants, filamentous fungi, bacteria, and yeast. Due to the wide commercial use of pectinase, one ha
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/04/2012
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10. Novel GATA5 loss-of-function mutations underlie familial atrial fibrillation
OBJECTIVE: This study aimed to identify novel GATA5 mutations that underlie familial atrial fibrillation. METHODS: A total of 110 unrelated patients with familial atrial fibrillation and 200 unrelated, ethnically matched healthy controls were recruited. The entire coding region of the GATA5 gene was sequenced in 110 atrial fibrillation probands. The availabl
Clinics. Publicado em: 2012-12
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11. Identification of coffee WRKY transcription factor genes and expression in resistance responses to pathogens.
In plants, WRKY proteins are a group of transcription factors existing as a gene superfamily that play important roles in regulation of defense response pathways. To assess the diversity of this protein family in coffee (Coffea spp.), data mining methods were used on a set of around 200,000 coffee expressed sequence tags. A total of 53 different putative WRK
TREE GENETICS & GENOMES. Publicado em: 2011
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12. Identification of coffee WRKY transcription factor genes and expression in resistance responses to pathogens.
In plants, WRKY proteins are a group of transcription factors existing as a gene superfamily that play important roles in regulation of defense response pathways. To assess the diversity of this protein family in coffee (Coffea spp.), data mining methods were used on a set of around 200,000 coffee expressed sequence tags. A total of 53 different putative WRK
TREE GENETICS & GENOMES. Publicado em: 2011