Sleep Rebound
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. Paradoxical sleep deprivation is related to muscle atrophy and damages muscle recovery / A privação de sono paradoxal em ratos está associada a atrofia muscular e déficit na recuperação muscular
Introduction: Paradoxical sleep deprivation (PSD) in rats is able to induce reductions in body mass and body fat, due to increased secretion of pituitary-adrenal axis hormones. Considering that PSD is also associated with a decrease in anabolic hormones, skeletal muscle can also be strongly influenced, causing atrophy damaging its recovery after a lesion. Ob
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/07/2011
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2. Effects of cocaine, methamphetamine and modafinil challenge on sleep rebound after paradoxical sleep deprivation in rats
Sleep loss is both common and critically relevant to our society and might lead to the abuse of psychostimulants such as amphetamines, cocaine and modafinil. Since psychoactive substance abuse often occurs within a scenario of sleep deficit, the purpose of this investigation was to compare the sleep patterns of rats challenged with cocaine (7 mg/kg, ip), met
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-01
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3. O papel do sistema dopaminérgico nigroestriatal na neurobiologia do sono / The role of the dopaminergic nigrostriatal system in the sleep neurobiology.
Dopamine (DA) is critically involved in regulating neural processes responsible for complex movements and emotions. Alterations in central dopaminergic neurotransmission have been implicated in important neurological and psychiatric disorders such as Parkinsons disease (PD) and schizophrenia. In addition, DA has recently been recognized as instrumental in th
Publicado em: 2008
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4. Medications for the Treatment of Sleep Disorders: An Overview
Sleep disorders can be divided into those producing insomnia, those causing daytime sleepiness, and those disrupting sleep. Transient insomnia is extremely common, afflicting up to 80% of the population. Chronic insomnia affects 15% of the population. Benzodiazepines are frequently used to treat insomnia; however, there may be a withdrawal syndrome with rapi
Physicians Postgraduate Press.
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5. Inhibition of sleep in rats by inorganic selenium compounds, inhibitors of prostaglandin D synthase.
Prostaglandin (PG) D2 has been postulated to be an endogenous sleep-promoting factor in rats, and SeCl4 and Na2SeO3 recently have been shown to inhibit the PGD synthase (prostaglandin-H2 D-isomerase, EC 5.3.99.2) activity of rat brain. The effect of these selenium compounds on sleep-wake activities was examined in freely moving rats along with their effects
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6. Emergent spindle oscillations and intermittent burst firing in a thalamic model: specific neuronal mechanisms.
The rhythmogenesis of 10-Hz sleep spindles is studied in a large-scale thalamic network model with two cell populations: the excitatory thalamocortical (TC) relay neurons and the inhibitory nucleus reticularis thalami (RE) neurons. Spindle-like bursting oscillations emerge naturally from reciprocal interactions between TC and RE neurons. We find that the net
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7. Serotonin hyperpolarizes cholinergic low-threshold burst neurons in the rat laterodorsal tegmental nucleus in vitro.
Serotonergic suppression of cholinergic neuronal activity implicated in the regulation of rapid eye movement sleep and its associated phenomenon, pontogeniculooccipital waves, has long been postulated, but no direct proof has been available. In this study, intracellular and whole-cell patch-clamp recording techniques were combined with enzyme histochemistry
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8. Mechanisms of long-lasting hyperpolarizations underlying slow sleep oscillations in cat corticothalamic networks.
1. To explore the nature of the long-lasting hyperpolarizations that characterize slow oscillations in corticothalamic circuits in vivo, intracellular recordings were obtained under ketamine-xylazine anaesthesia from cortical (Cx) cells of the cat precruciate motor cortex, thalamic reticular (RE) cells from the rostrolateral sector, and thalamocortical (TC)
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9. Spindle oscillation in cats: the role of corticothalamic feedback in a thalamically generated rhythm.
1. Spindles represent an oscillatory activity (7-14 Hz) of the electroencephalogram (EEG) originating in the thalamus and appearing during early stages of sleep. We investigated: (i) the phase relations between thalamic and cortical neurons during this rhythm; (ii) the patterns of spindles under different anaesthetics and their modifications at various level