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Ultrastructural evaluation of the radioprotective effect of sodium selenite on submandibular glands in rats

The aim of this study was to evaluate the radioprotector effect of sodium selenite on the ultrastructure of submandibular glands in rats. Fifty-seven male albino Wistar rats were randomized to 4 groups: control, irradiated, sodium selenite and irradiated/sodium selenite. The anim...

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Avaliação ultra-estrutural do efeito radioprotetor do selenito de sodio em glandulas submandibulares de ratos

The radioprotective effect of sodium selenite in the secretory cells of submandibular glands of rats was assessed by ultrastructural analysis. A total of 57 rats were used, which were divided into four experimental groups: control, irradiated, sodium selenite and sodium selenite/...

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Protective Effects of Sodium Selenite and Vitamin E on Mercuric Chloride-Induced Cardiotoxicity in Male Rats

This study was designed to investigate the protective effects of sodium selenite and/or vitamin E against mercuric chloride-induced cardiotoxicity. Male Wistar rats (n=48, 310±10 g) were administered mercuric chloride (1.0 mg/kg bw), sodium selenite (0.25 mg/kg bw), vitamin E (10...

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Lead Nitrate Induced Testicular Toxicity in Diabetic and Non-Diabetic Rats: Protective Role of Sodium Selenite

Among heavy met als, lead is one of the common pollutants found in the environment and biological system. In the present study, streptozotocin-induced diabetic and normal non-diabetic male Wistar rats were given sodium selenite (1.0 mg/kg bw), lead nitrate (22.5 mg/kg bw) and sod...

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Inhibitory Action of Selenite on Escherichia coli, Proteus vulgaris, and Salmonella thompson1

Weiss, K. F. (Iowa State University, Ames), J. C. Ayres, and A. A. Kraft. Inhibitory action of selenite on Escherichia coli, Proteus vulgaris, and Salmonella thompson. J. Bacteriol. 90:857–862. 1965.—The resistance of three microorganisms, Escherichia coli (ISU-41), Proteus vulga...

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Detection of Selenium Deposits in Escherichia coli by Electron Microscopy

Cells of Escherichia coli will reduce sodium selenite to elemental selenium. Examination by electron microscopy of E. coli cultures grown in the presence of sodium selenite show selenium deposited on the cell membrane and cell wall but not in the cytoplasm....

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75Se-sodium selenite as a diagnostic aid in the assessment of peripheral pulmonary opacities.

To establish or exclude the diagnosis of bronchial carcinoma a series of 43 patients with peripheral pulmonary opacities was studied by lung scanning after intravenous injection of 75Se-sodium selenite. A diagnosis was ultimately obtained in all patients. The incidence of both fa...

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Freshwater Bacteria Can Methylate Selenium through the Thiopurine Methyltransferase Pathway

Involvement of the bacterial thiopurine methyltransferase (bTPMT) in natural selenium methylation by freshwater was investigated. A freshwater environment that had no known selenium contamination but exhibited reproducible emission of dimethyl selenide (DMSe) or dimethyl diseleni...

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Vitamin E and Sodium Selenite Against Mercuric Chloride-Induced Lung Toxicity in the Rats

The aim of the present study was to elucidate the possible protective role of vitamin E and / or sodium selenite on mercuric chloride-induced oxidative stress and histopathological changes in the lung tissue of the rats. Adult male albino Wistar rats were exposed to mercuric chlo...

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A Novel Selenite- and Tellurite-Inducible Gene in Escherichia coli

Selenium is both an essential and a toxic trace element, and the range of concentrations between the two is extremely narrow. Although tellurium is not essential and is only rarely found in the environment, it is considered to be extremely toxic. Several hypotheses have been prop...

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Phase-separation inhibitors and prevention of selenite cataract.

The variation of the phase-separation temperature (Tc) was studied in lenses during formation of cataracts induced by a subcutaneous injection of sodium selenite. In normal control animals, the Tc decreased monotonically with increasing age. Approximately 2 days after administrat...

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Avaliação do efeito do selenito de sódio em dentes de filhotes de ratas irradicadas / Evaluation of sodium selenite effect on offspring teeth of irradiated female rats

The aim of this study was to evaluate the sodium selenite effect on offspring molars of irradiated female rats. For this purpose, twenty pregnant female rats were used and divided into four experimental groups: control, selenium, irradiated and selenium-irradiated. The animals of...

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Avaliação do efeito radioprotetor do selenito de sodio no processo de reparação tecidual : estudo experimental em ratos

The aim of this study was to evaluate the Sodium Selenite as protection substance. It were made rectangular wounds (2,5 X 1,5 cm) in the dorsal region of the rats, in order to stimulate the growing of the repair process. The rats were then divided into four groups as follows: con...

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Protective effect of sodium selenite on genotoxicity to human whole blood cultures induced by aflatoxin B1

The aim of this study was to investigate the effects of selenium and aflatoxin on human whole blood cultures (WBC) in relation to induction of sister-chromatid exchange (SCE). Results showed that the frequency of SCEs in peripheral lymphocytes was significantly increased by the d...

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Selenium as Inducer of Glutathione Peroxidase in low-CO2-Grown Chlamydomonas reinhardtii1

Culture of the green alga Chlamydomonas reinhardtii in the medium containing sodium selenite caused the activity of ascorbate peroxidase to disappear and the appearance of glutathione peroxidase. The induced maximum activity of glutathione peroxidase reached 350 micromole (millig...

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Avaliação do efeito radioprotetor do selenito de sodio na reparação ossea alveolar de ratos / Evaluation of the radioprotector effect of sodium selenite on the alveolar wound healing in rats

The aim of this study was evaluate the radioprotective effect of sodium selenite on the socket healing in rats. For this purpose, one hundred male rats were divided in four experimental groups: control, selenium, irradiated and selenium irradiated. All animals were submitted to u...

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Efeito do selenito de sodio na reparação ossea em tibias de ratos irradiados

Considering that the ionizing radiation may cause deleterious effects on the process of tissue repair and sodium selenite is an antioxidant agent, acting against the free radicals in the organism, this study aimed at evaluating the radioprotective effect of sodium selenite on the...

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Protective effect of sodium selenite against the genotoxicity of aflatoxin B1 in human whole blood cultures

This study was designed to investigate the effects of selenium and aflatoxin on human whole blood cultures (WBC) in relation to induction of sister-chromatid exchange (SCE). The results showed that the frequency of SCEs in peripheral lymphocytes was significantly increased by the...

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Effects of antioxidants on oxidant-induced sister chromatid exchange formation.

Stimulated human phagocytes produce sister chromatid exchanges in cultured mammalian cells by a mechanism involving oxygen metabolites. Experiments were designed to determine whether antioxidants inhibit this process. Superoxide dismutase, catalase, and hydroxyl radical scavenger...

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Enhanced Immunoglobulin M and Immunoglobulin G Antibody Titers in Mice Fed Selenium

Mice fed diets supplemented with selenium (sodium selenite) immunologically respond to the sheep red blood cell antigen by producing enhanced immunoglobulin M and immunoglobulin G antibody titers....

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Radioprotective Effect of Sodium Selenite on Mandible of Irradiated Rats

Resumo O propósito deste estudo foi testar o efeito radioprotetor do selênio na microarquitetura óssea de mandíbulas de ratos irradiados. Quarenta ratos foram separados em 4 grupos com 10 animais: grupo controle (GC), grupo irradiado (GI), grupo selenito de sódio (SSG) e grupo se...

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