Artigos científicos, teses e dissertações
Publicados nas melhores instituições de ensino

An Analysis of the Cost-of-Selection Concept

It is shown for a continuous haploid model that the common standard assumptions used in calculating the cost of gene substitution, namely, large constant population size and small constant selective value, are unnecessary. Population size may fluctuate during the course of substi...

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Comparison of the new miniature Wright peak flow meter with the standard Wright peak flow meter.

Preproduction and current models of the miniature Wright peak flow meter have been compared with the standard Wright peak flow meter on normal and abnormal subjects. Early problems in production appear to have been overcome, and the current model agrees to within 3% with the stan...

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Pharmacokinetic Properties In Silico Modeling for New Chemical Entities Evaluation. / Modelagem In silico de propriedades farmacocinéticas para a avaliação de candidatos a novos fármacos

The pharmacokinetic (PK) processes of absorption, distribution, metabolism and excretion (ADME), have been identified as one of the major causes of new chemical entities (NCEs) failure in early clinical trials. In silico models are receiving increased attention in recent years fr...

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Influence of elastic recovery time on the Dimensional Stability of Polydimethylsiloxane (PDS)

The aim of this study was to determine the influence from the recovering time on the dimensional stability of polydimethylsiloxane (Speedex, Coltène/Whaledent Company, Altstätten, Switzerland) prior to type IV dental stone pouring. The double impression technique was utilized wit...

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Comparisons of standard curve-fitting methods to quantitate Neisseria meningitidis group A polysaccharide antibody levels by enzyme-linked immunosorbent assay.

We examined several of the more commonly used models (log-log, two forms of the logit-log, and the four-parameter logistic-log transformations) for forming standard or calibration curves by using a standardized enzyme-linked immunosorbent assay (ELISA). Assay range, accuracy, and...

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MDAONTO: um processo MDA de desenvolvimento de software com foco em ontologias

Model Driven Architecture (MDA) software development standard follows a set of guidelines, which can promote substantial benefits in design of a new system. In this sense, using tools of this paradigm and the automated generation code, in several programming languages, it is poss...

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Comparison between known propagation models using least squares tuning algorithm on 5.8 GHz in Amazon region cities

This paper presents a performance comparison between known propagation Models through least squares tuning algorithm for 5.8 GHz frequency band. The studied environment is based on the 12 cities located in Amazon Region. After adjustments and simulations, SUI Model showed the sma...

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Um modelo referencia de objetos para sistemas de bancos de dados

An analysis over existing object models of OODBSs (Object Oriented Database System) shows the absence of a standard. This flaw limits the portability and interoperability of OODBSs, harming its endorsement, therefore demotivating its use in the market. Aiming for a solution to th...

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THE EM ALGORITHM FOR STANDARD STOCHASTIC FRONTIER MODELS

ABSTRACT The Expectation-Maximization (EM) algorithm is developed for the stochastic frontier models most used in practice with cross-section data. The resulting algorithms can be easily programmed into a computer and are shown to be worthy alternatives to general-purpose optimiz...

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Estimating Poisson pseudo-maximum-likelihood rather than log-linear model of a log-transformed dependent variable

Abstract Purpose The purpose of this study is to account for a recent non-mainstream econometric approach using microdata and how it can inform research in business administration. More specifically, the paper draws from the applied microeconometric literature stances in favor o...

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Estudo comparativo entre metaheutísticas populacionais com tamanho da população variável

This work introduces four novel population-based heuristic algorithms, whose population size varies along the execution, which are aimed at solving problems of search and numerical optimization. These algorithms are extensions of the standard models of two metaheuristics recently...

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Modeling and optimization of populations subject to time-dependent mutation.

It has become clear that many organisms possess the ability to regulate their mutation rate in response to environmental conditions. So the question of finding an optimal mutation rate must be replaced by that of finding an optimal mutation schedule. We show that this task cannot...

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Models of triple-stranded polynucleotides with optimised stereochemistry.

Detailed models are presented for the triple-stranded polynucleotide helices of poly (U)-poly (A)-poly (U) (two forms), poly (U)-poly d (A) -poly (U), poly d(C)-poly d(I)-poly d(C), poly d(T)-polyd(A)-poly d(T) and poly (I)-poly (A)-poly (I). The models were genrated using a comp...

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Critical behavior of ising models with random long-range (small-world) interactions

The critical scaling behavior of Ising models with long range interactions is studied. These long-range interactions, when imposed in addition to interactions on a regular lattice, lead to small world graphs. Large-scale Monte Carlo simulations, together with finite-size scaling,...

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Evolutionary Analyses of DNA Sequences Subject to Constraints on Secondary Structure

Evolutionary models appropriate for analyzing nucleotide sequences that are subject to constraints on secondary structure are developed. The models consider the evolution of pairs of nucleotides, and they incorporate the effects of base-pairing constraints on nucleotide substitut...

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Mutation-Selection Balance at a Modifier-of-Imprinting Locus

We propose a pair of population genetic models for a modifier-of-imprinting locus for which different genotypes imprint different proportions of an imprintable target locus in their gametes. The two models examine the situations in which imprinting is advantageous or disadvantage...

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Improvement of Wald residual in generalized linear models / Melhoramento do resíduo de Wald em modelos lineares generalizados

The theory of generalized linear models is very used in statistics, not only for modeling data normally distributed, but in the modeling of data whose distribution belongs to the exponential family of distributions. Some examples are binomial, gamma and inverse Gaussian distribut...

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RISCO SOBERANO, VOLATILIDADE E PADRÃO-OURO: 1870¿1930 / SOVEREIGN RISK, VOLATILITY AND THE GOLD STANDARD: 1870-1930

This research documents the relationship between sovereign risk volatility and gold standard adherence in the classical period comprised between 1870 and 1914. The application the econometric model of FCGARCH (or Flexible Coefficient GARCH) provides evidence that regimes of low v...

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