It is shown for a continuous haploid model that the common standard assumptions used in calculating the cost of gene substitution, namely, large constant population size and small constant selective value, are unnecessary. Population size may fluctuate during the course of substi...
Ver documentoPreproduction and current models of the miniature Wright peak flow meter have been compared with the standard Wright peak flow meter on normal and abnormal subjects. Early problems in production appear to have been overcome, and the current model agrees to within 3% with the stan...
Ver documentoThe pharmacokinetic (PK) processes of absorption, distribution, metabolism and excretion (ADME), have been identified as one of the major causes of new chemical entities (NCEs) failure in early clinical trials. In silico models are receiving increased attention in recent years fr...
Ver documentoThe aim of this study was to determine the influence from the recovering time on the dimensional stability of polydimethylsiloxane (Speedex, Coltène/Whaledent Company, Altstätten, Switzerland) prior to type IV dental stone pouring. The double impression technique was utilized wit...
Ver documentoWe examined several of the more commonly used models (log-log, two forms of the logit-log, and the four-parameter logistic-log transformations) for forming standard or calibration curves by using a standardized enzyme-linked immunosorbent assay (ELISA). Assay range, accuracy, and...
Ver documentoModel Driven Architecture (MDA) software development standard follows a set of guidelines, which can promote substantial benefits in design of a new system. In this sense, using tools of this paradigm and the automated generation code, in several programming languages, it is poss...
Ver documentoThis paper presents a performance comparison between known propagation Models through least squares tuning algorithm for 5.8 GHz frequency band. The studied environment is based on the 12 cities located in Amazon Region. After adjustments and simulations, SUI Model showed the sma...
Ver documentoAn analysis over existing object models of OODBSs (Object Oriented Database System) shows the absence of a standard. This flaw limits the portability and interoperability of OODBSs, harming its endorsement, therefore demotivating its use in the market. Aiming for a solution to th...
Ver documentoABSTRACT The Expectation-Maximization (EM) algorithm is developed for the stochastic frontier models most used in practice with cross-section data. The resulting algorithms can be easily programmed into a computer and are shown to be worthy alternatives to general-purpose optimiz...
Ver documentoAbstract Purpose The purpose of this study is to account for a recent non-mainstream econometric approach using microdata and how it can inform research in business administration. More specifically, the paper draws from the applied microeconometric literature stances in favor o...
Ver documentoThis work introduces four novel population-based heuristic algorithms, whose population size varies along the execution, which are aimed at solving problems of search and numerical optimization. These algorithms are extensions of the standard models of two metaheuristics recently...
Ver documentoIt has become clear that many organisms possess the ability to regulate their mutation rate in response to environmental conditions. So the question of finding an optimal mutation rate must be replaced by that of finding an optimal mutation schedule. We show that this task cannot...
Ver documentoDetailed models are presented for the triple-stranded polynucleotide helices of poly (U)-poly (A)-poly (U) (two forms), poly (U)-poly d (A) -poly (U), poly d(C)-poly d(I)-poly d(C), poly d(T)-polyd(A)-poly d(T) and poly (I)-poly (A)-poly (I). The models were genrated using a comp...
Ver documentoThe critical scaling behavior of Ising models with long range interactions is studied. These long-range interactions, when imposed in addition to interactions on a regular lattice, lead to small world graphs. Large-scale Monte Carlo simulations, together with finite-size scaling,...
Ver documentoEvolutionary models appropriate for analyzing nucleotide sequences that are subject to constraints on secondary structure are developed. The models consider the evolution of pairs of nucleotides, and they incorporate the effects of base-pairing constraints on nucleotide substitut...
Ver documentoWe propose a pair of population genetic models for a modifier-of-imprinting locus for which different genotypes imprint different proportions of an imprintable target locus in their gametes. The two models examine the situations in which imprinting is advantageous or disadvantage...
Ver documentoThe theory of generalized linear models is very used in statistics, not only for modeling data normally distributed, but in the modeling of data whose distribution belongs to the exponential family of distributions. Some examples are binomial, gamma and inverse Gaussian distribut...
Ver documentoThis research documents the relationship between sovereign risk volatility and gold standard adherence in the classical period comprised between 1870 and 1914. The application the econometric model of FCGARCH (or Flexible Coefficient GARCH) provides evidence that regimes of low v...
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