Steroid Receptors
Mostrando 1-12 de 459 artigos, teses e dissertações.
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1. Classic and current concepts in adrenal steroidogenesis: a reappraisal
ABSTRACT Adrenal steroid biosynthesis and its related pathology are constant evolving disciplines. In this paper, we review classic and current concepts of adrenal steroidogenesis, plus control mechanisms of steroid pathways, distribution of unique enzymes and cofactors, and major steroid families. We highlight the presence of a “mineralocorticoid (MC) pat
Archives of Endocrinology and Metabolism. Publicado em: 2022
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2. Vitamin D, vitamin D binding protein, vitamin D receptor levels and cardiac dysautonomia in patients with multiple sclerosis: a cross-sectional study
RESUMO A vitamina D é um hormônio esteroide pleiotrópico que modula o equilíbrio autonômico. Sua deficiência tem sido descrita como fator de risco ambiental para esclerose múltipla (EM). O objetivo deste estudo foi investigar os níveis séricos de vitamina D, proteína de ligação à vitamina D (VDBP) e receptor de vitamina D (VDR) e avaliar a disau
Arq. Neuro-Psiquiatr.. Publicado em: 10/01/2020
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3. Melatonin effects on ovarian follicular cells: a systematic review
RESUMO A melatonina é conhecida por seus efeitos no sono e no sistema reprodutivo dos mamíferos. Este último tem receptores de melatonina tipos 1 e 2, que atuam para regular, entre outras coisas, o AMP cíclico. Apesar de todos os dados da literatura, ainda não há um conhecimento sólido ou uma compreensão clara da ação do hormônio na fisiologia das
Rev. Assoc. Med. Bras.. Publicado em: 12/09/2019
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4. Hypothalamic transcriptional expression of the kisspeptin system and sex steroid receptors differs among polycystic ovary syndrome rat models with different endocrine phenotypes
OBJECTIVES: Polycystic ovary syndrome is a heterogeneous endocrine disorder that affects reproductive-age women. The mechanisms underlying the endocrine heterogeneity and neuroendocrinology of polycystic ovary syndrome are still unclear. In this study, we investigated the expression of the kisspeptin system and gonadotropin-releasing hormone pulse regulator
Clinics. Publicado em: 2017-08
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5. Expression of estrogen and progesterone receptors in astrocytomas: a literature review
Gliomas are the most common type of primary central nervous system neoplasm. Astrocytomas are the most prevalent type of glioma and these tumors may be influenced by sex steroid hormones. A literature review for the presence of estrogen and progesterone receptors in astrocytomas was conducted in the PubMed database using the following MeSH terms: “estrogen
Clinics. Publicado em: 2016-08
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6. Estrogen and progesterone receptors in endometrial polyps of women exposed and not exposed to tamoxifen and in atrophic endometrium / Receptores de estrógeno e progesterona em pólipos endometriais de usuárias e não usuárias de tamoxifeno e no endométrio atrófico
Introduction: Tamoxifen has been used for the treatment of strogen receptor-positive breast cancer. The effect of tamoxifen in breast cancer is the it inhibition cancer cell growth by competitive antagonism with strogen for strogen receptor (ER). The mechanism of action of tamoxifen in this receptor varies among different tissues, with antagonist effect (e.g
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2012
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7. Diretrizes para prevenção e tratamento da osteoporose induzida por glicocorticoide
Os glicocorticoides (GC) são prescritos por praticamente todas as especialidades médicas, e cerca de 0,5% da população geral do Reino Unido utiliza esses medicamentos. Com o aumento da sobrevida dos pacientes com doenças reumatológicas, a morbidade secundária ao uso dessa medicação representa um aspecto importante que deve ser considerado no manejo
Revista Brasileira de Reumatologia. Publicado em: 2012-08
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8. Controle hormonal da próstata feminina do gerbilo sob influência de múltiplas prenhezes e reposição hormonal / Hormonal control of the gerbil s female prostate : influence of multiple pregnancies and hormone replacement
The gerbil female prostate is located paraurethrally and has all the main histological components of the male prostate, like secretor epithelium and fibromuscular stroma. This gland, like the prostate in males, is targeted by testosterone action, which promotes morphofunctional development. Furthermore, estrogens are required to maintain the male and female
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/01/2011
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9. Differential binding with ERα and ERβ of the phytoestrogen-rich plant Pueraria mirifica
Variations in the estrogenic activity of the phytoestrogen-rich plant, Pueraria mirifica, were determined with yeast estrogen screen (YES) consisting of human estrogen receptors (hER) hERα and hERβ and human transcriptional intermediary factor 2 (hTIF2) or human steroid receptor coactivator 1 (hSRC1), respectively, together with the β-galactosidase expres
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-02
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10. Desenvolvimento da próstata masculina e feminina do gerbilo da Mongólia submetido à exposição no período embriofetal e pós-natal de etinilestradiol / Development of male and female prostate of the Mongolian gerbil submitted to the exposure embryofetal period and postnatal ethinylestradiol
In males, prostatic morphogenesis is an event controlled by androgens, which act directly via paracrine factors secreted by the mesenchyme. In females, the embryological development of the prostate appears to occur in environment low levels of steroid hormones, but the presence of these hormones in the adult life induces differentiation and secretory activit
Publicado em: 2010
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11. Cycle modulation of insulin-like growth factor-binding protein 1 in human endometrium
Endometrium is one of the fastest growing human tissues. Sex hormones, estrogen and progesterone, in interaction with several growth factors, control its growth and differentiation. Insulin-like growth factor 1 (IGF-1) interacts with cell surface receptors and also with specific soluble binding proteins. IGF-binding proteins (IGF-BP) have been shown to modul
Publicado em: 2010
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12. Peptídeos antimicrobianos: síntese, ensaios biológicos, estudos termodinâmicos e análise estrutural por RMN em meios biomiméticos
Many organisms employ noxious chemicals (e.g., amines, steroid derivatives, alkaloids and peptides) to defend themselves against predators and pathogenic microrganisms. Among these chemical agents stand out peptides that can be found in a wide variety of organisms including bacteria, fungi, plants, insects, fish, amphibians,arachnids and mammals. The vast ma
Publicado em: 2010