Substrate Inhibition
Mostrando 1-12 de 1545 artigos, teses e dissertações.
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1. ASSESSMENT OF α-AMYLASE INHIBITION ACTIVITY BY AN OPTIMIZED AND VALIDATED IN VITRO MICROSCALE METHOD
Metabolic disorders, including hyperglycemia, characterize type-2 diabetes. One of the treatment methods used for postprandial hyperglycemia includes using potential therapeutic agents to inhibit α-amylase activity. This study utilized fractional design and the simplex method to optimize in vitro microscale assay inhibition conditions using Miller’s react
Química Nova. Publicado em: 2022
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2. 2-(Pyridin-4yl)benzothiazole and Its Benzimidazole-Analogue: Biophysical and in silico Studies on Their Interaction with Urease and in vitro Anti-Helicobacter pylori Activities
In this study, the interaction between benzothiazole (BTA, concentration of a drug required for 50% inhibition in vitro (IC50) = 0.77 mM) and benzimidazole (BIA, IC50 = 2.14 mM) with urease was quantitatively assessed, using UV-Vis, molecular fluorescence, and circular dichroism. The results showed that both compounds interact with urease by a static fluores
Journal of the Brazilian Chemical Society. Publicado em: 2022
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3. New Synthetic Quinolines as Cathepsin K Inhibitors
Cathepsin K is a papain-like cysteine protease and is responsible for collagen degradation in bone tissue and thus represents an important target for the development of new therapies for treating diseases such as osteoporosis. Quinolines are an important class of heterocyclic molecular leads with a great pharmacological potential and represent a relevant sca
J. Braz. Chem. Soc.. Publicado em: 2020-08
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4. Morphology of yellow passion fruit seedlings submitted to triazole induced growth inhibition
RESUMO A restrição do vigor vegetativo de mudas pode ser uma estratégia para otimização da modulação frente à estresses bióticos e abióticos após o transplantio. O objetivo desse estudo foi verificar se os parâmetros morfológicos de mudas de maracujazeiro amarelo (Passiflora edulis) são afetados pela restrição do crescimento com aplicação d
Ciênc. agrotec.. Publicado em: 20/12/2019
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5. Residues of Invasive Forage Species Inhibits the Growth of Caryocar brasiliense
RESUMO: O crescimento de mudas de espécies nativas pode ser afetado por substâncias alelopáticas liberadas por espécies forrageiras invasivas principalmente em áreas de recomposição natural. Objetivou-se nesta pesquisa avaliar as características de crescimento do pequizeiro influenciadas por concentrações de resíduos vegetais das espécies forrage
Planta daninha. Publicado em: 02/12/2019
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6. LIPIDS AS COMPETITIVE INHIBITORS OF SUBTILISIN CARLSBERG IN THE ENZYMATIC HYDROLYSIS OF PROTEINS IN RED TILAPIA (Oreochromis sp.) VISCERA: INSIGHTS FROM KINETIC MODELS AND A MOLECULAR DOCKING STUDY
Abstract Protein hydrolysis can improve food’s nutritional, techno-functional and biological properties, which can increase the possibilities of application in industry. The objective of this research article was to study the effect of lipids on the enzymatic kinetics of red tilapia viscera (RTV) hydrolysis with subtilisin Carlsberg. The RTV were hydrolyze
Braz. J. Chem. Eng.. Publicado em: 30/09/2019
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7. Using White Star (Nymphoides humboldtiana) for lake landscaping
RESUMO Estrela Branca (Nymphoides humboldtiana), espécie nativa da flora brasileira, proveniente de ambientes aquáticos, foi selecionada visando seu uso como planta ornamental em lagos. Plantas de Estrela Branca foram submetidas a dois níveis de água (nível alto, até 30 cm de lâmina de água e nível baixo, até a saturação do substrato) e duas inte
Hortic. Bras.. Publicado em: 18/07/2019
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8. BIOTECHNOLOGICAL APPLICATION OF SURFACE MODIFIED CERIUM OXIDE NANOPARTICLES
ABSTRACT Re-engineering of chemical materials at the nanoscale level that employ modification and improvement in their physical and chemical properties has been constantly pursued for application in biomedical and biotechnology industries. Moreover, immobilization of catalysts on these bio/chemically modified nanomaterials improved the performance of enzymes
Braz. J. Chem. Eng.. Publicado em: 15/07/2019
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9. The Anti-melanogenesis Activities of Some Selected Brown Macroalgae from Northern Coasts of the Persian Gulf
Abstract Melanogenesis is a biological process which led to the synthesis of melanin pigment. Abnormal melanin production results in melasma, solar lentigo, post inflammatory melanoderma, etc. In this study, we examined the potential inhibitory effects of 17 brown macroalgae from Persian Gulf on melanogenesis. The effects of various concentrations (100, 250
Braz. arch. biol. technol.. Publicado em: 13/06/2019
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10. The association between social skills deficits and family history of mood disorder in bipolar I disorder
Objective: To compare social skills and related executive functions among bipolar disorder (BD) patients with a family history of mood disorders (FHMD), BD patients with no FHMD and healthy control (HCs). Methods: We evaluated 20 euthymic patients with FHMD, 17 euthymic patients without FHMD, and 31 HCs using the Social Skills Inventory (SSI) and a neurops
Rev. Bras. Psiquiatr.. Publicado em: 26/03/2018
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11. Evaluation of the anticorrosion performance of peel garlic extract as corrosion inhibitor for ASTM 1020 carbon steel in acidic solution
ABSTRACT Metallic corrosion can be delayed using corrosion inhibitors. However, several industrial corrosion inhibitors are toxic and harmful to the environment and to the human health. In this context, in the last decades, research has been developed to investigate the performance of low toxicity corrosion inhibitors as green inhibitors obtained from vegeta
Matéria (Rio J.). Publicado em: 10/08/2017
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12. Optimization of solid-state fermentation for bioherbicide production by Phoma sp .
Abstract In this work the bioherbicide production from Phoma sp. by solid-state fermentation was optimized. Agroindustrial residues such as bagasse, soybean bran and corn steep liquor were used as substrate. The bioherbicide was extracted from the fermented solid and the supernatant was applied for the control of the target plant. The evaluated responses in
Braz. J. Chem. Eng.. Publicado em: 2017-04