Subthalamic Nucleus
Mostrando 1-12 de 27 artigos, teses e dissertações.
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1. How is cognition in subthalamic nucleus deep brain stimulation Parkinson’s disease patients?
Resumo As deficiências nas funções cognitivas, como memória, função executiva, habilidades visuoespaciais e linguagem na doença de Parkinson (DP), estão cada vez mais chamando a atenção na literatura atual. Estudos dedicados a investigar a relação entre a estimulação cerebral profunda do núcleo subtalâmico (ECP-NST) e o funcionamento cognitiv
Dement. neuropsychol.. Publicado em: 09/12/2019
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2. Efeito da técnica de sobrearticulação na voz e na fala em indivíduos com doença de Parkinson após cirurgia de estimulação cerebral profunda
RESUMO Objetivo Verificar o efeito imediato e após 15 minutos da técnica de sobrearticulação de fala em indivíduos com doença de Parkinson, submetidos à estimulação cerebral profunda em núcleo subtalâmico, nos parâmetros de voz, fala e mímica facial. Métodos Participaram 29 sujeitos com diagnóstico médico de doença de Parkinson, sob tratam
Audiol., Commun. Res.. Publicado em: 05/09/2019
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3. Acoustic Voice Modifications in Individuals with Parkinson Disease Submitted to Deep Brain Stimulation
Abstract Introduction Subthalamic nucleus deep brain stimulation (STN-DBS) improvesmotor function in individuals with Parkinson disease (PD). The evidence about the effects of STN-DBS on the voice is still inconclusive. Objective To verify the effect of STN-DBS on the voice of Brazilian individuals with PD. Methods Sixteen participants were evaluated o
Int. Arch. Otorhinolaryngol.. Publicado em: 18/07/2019
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4. Systematic review of neuropsychological instruments used in subthalamic nucleus deep brain stimulation in Parkinson´s disease patients
RESUMO. Além do tratamento medicamentoso, a intervenção cirúrgica é uma alternativa aos pacientes com DP com déficits motores. A mais comum é a estimulação cerebral profunda do núcleo subtalâmico (ECP-NST). É extremamente importante realizar uma avaliação neuropsicológica em pacientes com ECP-NST, não apenas para identificar perdas relacionad
Dement. neuropsychol.. Publicado em: 18/06/2019
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5. Safety of transcranial direct current stimulation in a patient with deep brain stimulation electrodes
RESUMO Descrição: A estimulação transcraniana por corrente contínua (ETCC) tem sido investigada nos distúrbios de movimento, tornando-a uma alternativa terapêutica no contexto clínico. Contudo, não há consenso quanto aos protocolos mais apropriados na maioria dos casos e a presença de eletrodos de estimulação cerebral profunda (ECP) é geralmen
Arq. Neuro-Psiquiatr.. Publicado em: 2019-03
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6. Efeitos do envelhecimento sobre o sistema nitrérgico dos núcleos da base em humanos
Nitric oxide (NO) is a gaseous molecule that plays a role in a number of physiologic processes. The available evidence suggests that NO is a major neurotransmitter involved in motor control and emotion/behavior modulation. To investigate the distribution and morphology of the nitrergic system in human basal nuclei, we studied samples from the striatum, globu
Arq. Neuro-Psiquiatr.. Publicado em: 2014-10
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7. Lesion of the subthalamic nucleus reverses motor deficits but not death of nigrostriatal dopaminergic neurons in a rat 6-hydroxydopamine-lesion model of Parkinson's disease
The objective of the present study was to determine whether lesion of the subthalamic nucleus (STN) promoted by N-methyl- D-aspartate (NMDA) would rescue nigrostriatal dopaminergic neurons after unilateral 6-hydroxydopamine (6-OHDA) injection into the medial forebrain bundle (MFB). Initially, 16 μg 6-OHDA (6-OHDA group) or vehicle (artificial cerebrospinal
Publicado em: 2011
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8. Lesion of the subthalamic nucleus reverses motor deficits but not death of nigrostriatal dopaminergic neurons in a rat 6-hydroxydopamine-lesion model of Parkinson's disease
The objective of the present study was to determine whether lesion of the subthalamic nucleus (STN) promoted by N-methyl-D-aspartate (NMDA) would rescue nigrostriatal dopaminergic neurons after unilateral 6-hydroxydopamine (6-OHDA) injection into the medial forebrain bundle (MFB). Initially, 16 mg 6-OHDA (6-OHDA group) or vehicle (artificial cerebrospinal fl
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-01
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9. Effects of subthalamic nucleus stimulation and levodopa on the autonomic nervous system in Parkinson's disease
Dysfunctions of the autonomic nervous system (ANS) are common in Parkinson's disease (PD). Regarding motor disability, deep brain stimulation of the subthalamic nucleus (STN) is an effective treatment option in long lasting PD. The aims of this study were to examine whether STN stimulation has an influence on functions of the ANS and to compare these effects
BMJ Group.
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10. Pathological gambling after bilateral subthalamic nucleus stimulation in Parkinson disease
We describe a patient with advanced Parkinson's disease who developed pathological gambling within a month after successful bilateral subthalamic nucleus (STN) stimulation. There was no history of gambling. On neuropsychological testing, slight cognitive decline was evident 1 year after surgery. Stimulation of the most dorsal contact with and without medic
BMJ Group.
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11. Modeling facilitation and inhibition of competing motor programs in basal ganglia subthalamic nucleus–pallidal circuits
The motor symptoms of Parkinson's disease (PD) implicate the basal ganglia (BG) in some aspect of motor control, although the role the BG play in regulation of motor behavior is not completely understood. The modeling study presented here takes advantage of available cellular, systems, and clinical data on BG and PD to begin to build a biophysically based ne
National Academy of Sciences.
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12. The Electrocorticogram Signal Can Be Modulated With Deep Brain Stimulation of the Subthalamic Nucleus in the Hemiparkinsonian Rat
Electrocorticogram (ECoG) recordings of the 6-hydroxydopamine (6-OHDA)–lesioned parkinsonian rat have shown an increase in the power of cortical β-band (15–30 Hz) oscillations ipsilateral to the lesion. The power of these oscillations is decreased with dopamine agonist administration. Here, we demonstrate that stimulation of an electrode implanted in th
American Physiological Society.