Teratogenic Effects
Mostrando 1-12 de 44 artigos, teses e dissertações.
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1. Seroprevalence of Zika virus among blood donors before the epidemic in Barranquilla, Colombia, 2015-2016.
Abstract: The first cases of Zika virus infection in Colombia were reported and confirmed in October 2015. The objective of the study was estimate the seroprevalence of ZIKV infection during the pre-epidemic phase in Barranquilla, Colombia, and demonstrate the presence of virus before the Colombian Ministry of Health confirmed the first case. We conducted a
An. Acad. Bras. Ciênc.. Publicado em: 23/09/2019
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2. Oxidative Stress of in-Ovo Ochratoxin A Administered during Chick Embryonic Development
ABSTRACT The present work was carried out to study the effect of in-ovo injection of ochratoxin A (OTA) as an oxidative stress and its consequences on hepatic and kidney functions, thyroid activity, and histological examination of brain and liver in chicken embryos and subsequently in the hatching chicks. On the 10th day of incubation, one hundred and sixty-
Braz. J. Poult. Sci.. Publicado em: 09/05/2019
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3. Efeitos de extratos de Nierembergia veitchii (Hook) Solanaceae sobre a fertilidade de ratas e morfologia óssea dos fetos / The effects of Nierembergia veitchii (Hook) Solanaceae extracts in rat fertility and fetal skeleton morphology
Os efeitos da administração oral dos extratos aquoso (NvH2O), metanólico (NvmeOH), butanólico (Nvbut) e hexano (Nvhex), obtidos, seqüencialmente, de 500g de Nierembergia veitchii (planta seca), foram comparados aos obtidos com vitamina D3 (2,5mg.kg-1) e aos de um grupo controle (solução fisiológica - SF), quando administrados, durante todo o período
Publicado em: 2010
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4. Avaliação da toxicidade da Ipomoea carnea em caprinos durante o período perinatal: estudos de neuroteratologia / Evaluation of the toxicity of Ipomoea carnea in goats during postnatal period
Ipomoea carnea, a shrub plant, is a toxic plant largely distributed throughout Brazil and others topical countries. This plant possess swainsonine, an indolizidinic alkaloid as the most important active toxic principle, which promotes cellular accumulation of not metabolized oligossacarides, due to inhibition of acid or lisossomal αmanosidasis enzyme,
Publicado em: 2009
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5. AVALIAÇÃO DE NOVOS ANÁLOGOS DA TALIDOMIDA QUANTO A INIBIÇÃO DA PRODUÇÃO DE ÓXIDO NÍTRICO, CITOCINAS PRÓ-INFLAMATÓRIAS E EXPRESSÃO DE CD80 E CD86 EM MACRÓFAGOS
Thalidomide is used to treat various diseases including erythema nodosum leprosum (ENL), an inflammatory complication of leprosy. However, it has severe teratogenic activity and novel thalidomide analogues might be used to treat the disease without this severe side effect. A series of diamine compounds containing two hydrolyzed phthalimido structures were ch
Publicado em: 2009
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6. A model for prenatal toxicological studies in ruminants: evaluation of toxic effects caused by Senna occidentalis in goats / Proposta de modelo para o estudo de toxicologia perinatal em ruminantes: avaliação dos efeitos tóxicos da Senna occidentalis em caprinos
Senna occidentalis (So - formerly Cassia occidentalis), Fabaceae-Caesalpinoideae (Leguminosae) is a weed growing in pastures and in cultivated fields such as corn and soybeans in many tropical and subtropical areas worldwide. Many reports have shown that So is toxic to different animal species. Histologic lesions plant-related are degeneration skeltal and ca
Publicado em: 2008
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7. DESENVOLVIMENTO E VALIDAÇÃO DE MÉTODO PARA DETERMINAÇÃO DE ETILENOTIOURÉIA EM URINA EMPREGANDO HPLCUV / DEVELOPMENT AND VALIDATION METHOD FOR THE DETERMINATION OF ETHYLENETHIOUREA IN URINE BY HPLC-UV
In order to supply the world-wilde demand for food, it is essential to use the pesticides to protect the crops against pests and diseases. But the indiscriminate and injudicious use of these compounds have resulted in widespread contamination in food commodities and environment in all fields, increasing, this way, the preoccupation with chemical products use
Publicado em: 2008
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8. Desenvolvimento embrionário em ratas wistar prenhes submetidas ao ultra-som terapêutico de 3 MHz
Therapeutic ultrasound is widely used in different aesthetic treatment by young women, who can be irradiated during early gestation. Researches regarding the effects of therapeutic ultrasound on gestation present controversial results. Methodologies incompatible with clinical aspects are used and different methods and technics were employed. However none of
Publicado em: 2007
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9. Etanol, deficiência de ácido fólico e associação desses dois fatores durante a gestação de camundongos swiss / Etanol, Deficiency of Acid Fólico and Association Of these Two Factors During the Gestation of Swiss Mice
In spite of the well known teratogenic effect of ethanol, it is still the most consumed exogenous abuse substance by women of reproductive age. Ethanol also impairs the absorption, transport and metabolism of folic acid. The aim of this study was to investigate the effects of ethanol, dietary deficiency of folic acid and the association of both on the outcom
Publicado em: 2007
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10. Efeitos da ingestão do alcool durante a gestação na imunoexpressão do EGF na amelogenese e dentinogenese do 1º molar inferior de ratos
Previous studies have reported that the maternal exposure to alcohol reduces the maxilo-fadal development, including a delay in the formation and eruption of the tooth, as well as, enamel anomalies. The mechanisms of these deleterious effects are not fully clarified. The objective of this study was to analyze using polyclonal antibody of the Epidermal Growth
Publicado em: 2004
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11. Efeito de bloqueadores de canais de íons cálcio sobre espermatozóides e oócitos de hamsters fecundados in vivo e in vitro / Effects of calcium ion channel blockers on hamster spermatozoa and oocytes in in vivo and in vitro fertilization
Fertilization process is closely related with calcium ion. There are reports about voltage-dependent calcium ion channel blockers of anti-hypertension therapeutic use causing male infertility, but there are few reports about such effects on the oocyte. The main goal of this experiment was to check the influence of verapamil, nifedipine and diltiazem (L-type
Publicado em: 2004
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12. Adverse pregnancy outcome in rats following exposure to a Salacia reticulata (Celastraceae) root extract
The root extract of Salacia reticulata Wight (family: Celastraceae) is used in Sri Lanka by traditional practitioners as a herbal therapy for glycemic control even during pregnancy. It is recognized that some clinically used antidiabetic drugs have harmful effects on pregnancy but the effects of the S. reticulata root extract on reproductive outcome is unkno
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-07