Terbinafine
Mostrando 1-12 de 121 artigos, teses e dissertações.
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1. Deep dermatophytosis caused by Trichophyton rubrum in immunocompromised patients
Abstract In immunosuppressed patients, dermatophytosis can be more invasive, affecting the dermis and subcutaneous tissues. The authors describe the cases of two patients with kidney and heart transplanted, respectively, that developed a deep dermatophytosis caused by Trichophyton rubrum, confirmed by culture and DNA sequencing. Both patients had concomitant
Anais Brasileiros de Dermatologia. Publicado em: 2022
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2. Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide,
Abstract Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The authors report a case of fixed cutaneous sporotrichosis with therapeutic failure after 18 months of itraconazole and terbinafine associated with cryosurgery. The patient was cured after the introduction of saturated potassium iodide solution. Sporothrix b
An. Bras. Dermatol.. Publicado em: 2021-03
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3. Clinical and laboratory profile of urban sporotrichosis in a tertiary hospital in the city of São Paulo,
Abstract Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The authors report a case of fixed cutaneous sporotrichosis with therapeutic failure after 18 months of itraconazole and terbinafine associated with cryosurgery. The patient was cured after the introduction of saturated potassium iodide solution. Sporothrix b
An. Bras. Dermatol.. Publicado em: 2021-03
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4. Synergistic effect of terbinafine and amphotericin B in killing Fonsecaea nubica in vitro and in vivo
ABSTRACT Chromoblastomycosis is a chronic fungal infection. Itraconazole and terbinafine are the most recommended antifungal drugs for chromoblastomycosis, while amphotericin B is not usually recommended. A patient with chromoblastomycosis in our hospital showed poor clinical responses to itraconazole and terbinafine. The fungus isolated from the lesions o
Rev. Inst. Med. trop. S. Paulo. Publicado em: 19/06/2019
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5. In Vitro additive effect on griseofulvin and terbinafine combinations against multidrug-resistant dermatophytes
ABSTRACT Griseofulvin (GF) and terbinafine (TF) are commonly used drugs to treat dermatophytosis, a fungal infection of the skin. Today there is an increase in drug resistance to these antifungals which highlight the need for alternative synergistic therapies. Minimum Inhibitory Concentration (MIC) of GF and TF were determined against fungi clinical isolates
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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6. Minimal inhibitory concentration distributions and epidemiological cutoff values of five antifungal agents against Sporothrix brasiliensis
BACKGROUND Sporothrix brasiliensis is the most virulent sporotrichosis agent. This species usually responds to antifungal drugs, but therapeutic failure can occur in some patients. Antifungal susceptibility tests have been performed on this species, but no clinical breakpoints (CBPs) are available. In this situation, minimal inhibitory concentration (MIC) d
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-05
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7. Tinea faciei on the right eyebrow caused by Trichophyton interdigitale
Abstract Tinea faciei is a relatively uncommon dermatophyte infection entailing atypical clinical symptoms, usually misdiagnosed and treated with corticosteroids. The authors describe a case of tinea faciei on the right eyebrow caused by Trichophyton interdigitale. The patient was an 18-year-old girl, who had an inflammatory plaque with a scaly, pustular sur
An. Bras. Dermatol.. Publicado em: 2016-12
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8. Antifungal activity and mechanism of action of monoterpenes against dermatophytes and yeasts
Dermatomycosis causes highly frequent dermal lesions, and volatile oils have been proven to be promising as antifungal agents. The antifungal activity of geraniol, nerol, citral, neral and geranial (monoterpenes), and terbinafine and anidulafungin (control drugs) against seven opportunistic pathogenic yeasts and four dermatophyte species was evaluated by the
Rev. bras. farmacogn.. Publicado em: 2014-12
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9. Onychomycosis: clinical, mycological and in vitro susceptibility testing of isolates of Trichophyton rubrum
BACKGROUND: Onychomycosis or nail fungal infection is the most common nail disease. Despite the wide range of studies on this condition, it remains difficult to establish the correct diagnosis and effective treatment. OBJECTIVES: To evaluate the efficacy of classical laboratory methods for the diagnosis of onychomycosis, and the in vitro susceptibility
An. Bras. Dermatol.. Publicado em: 2014-07
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10. Arachidonic acid affects biofilm formation and PGE2 level in Candida albicans and non-albicans species in presence of subinhibitory concentration of fluconazole and terbinafine
Candida albicans utilizes arachidonic acid (AA) released during the course of infection (Candidiasis) from phospholipids of infected host cell membranes and synthesizes extracellular prostaglandin(s) which play an important role in hyphae formation and host cell damage. C. albicans biofilms secrete significantly more prostaglandin(s) and evidence suggests t
Braz J Infect Dis. Publicado em: 2014-06
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11. Microsporum spp. onychomycosis: disease presentation, risk factors and treatment responses in an urban population
BACKGROUND: Dermatophytes are the main causative agent of all onychomycosis, but genus Microsporum is infrequent and the risk of acquiring the infection is often associated with exposure to risk factors. OBJECTIVES: To describe clinical characteristics of onychomycosis due to Microsporum onychomycosis in an urban population. METHODS: This was a retrospe
Braz J Infect Dis. Publicado em: 2014-04
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12. Oral treatments for fungal infections of the skin of the foot
BACKGROUND: About 15% of the world population have fungal infections of the feet (tinea pedis or athlete's foot). There are many clinical presentations of tinea pedis, and most commonly, tinea pedis is seen between the toes (interdigital) and on the soles, heels, and sides of the foot (plantar). Plantar tinea pedis is known as moccasin foot. Once acquired,
Sao Paulo Med. J.. Publicado em: 2014