Therapeutical Application
Mostrando 1-12 de 26 artigos, teses e dissertações.
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1. Therapeutic evaluation of magnetic hyperthermia using Fe3O4-aminosilane-coated iron oxide nanoparticles in glioblastoma animal model
RESUMO Objetivo: Avaliar o potencial da técnica de magneto-hipertermia utilizando nanopartículas superparamagnéticas de óxido de ferro recobertas com aminosilana em modelo de tumores de glioblastoma. Métodos: As nanopartículas superparamagnéticas de óxido de ferro recobertas com aminosilana foram avaliadas quanto à sua estabilidade em meio aquoso
Einstein (São Paulo). Publicado em: 01/08/2019
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2. Protein PEGylation for the design of biobetters: from reaction to purification processes
The covalent attachment of polyethylene glycol (PEG) to therapeutical proteins is an important route to develop biobetters for biomedical, biotech and pharmaceutical industries. PEG conjugation can shield antigenic epitopes of the protein, reduce degradation by proteolytic enzymes, enhance long-term stability and maintain or even improve pharmacokinetic and
Braz. J. Pharm. Sci.. Publicado em: 08/11/2018
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3. Evaluation of prophylactic and therapeutic effects of sildenafil on acute radiation proctitis in rats
Abstract Purpose: To investigate the prophylactic and therapeutical effects of sildenafil in a model of acute radiation proctitis (ARP). Methods: All experimental procedures of this study was examined by histopathological, immunohistochemical and transmission electron microscopic analysis. Results: Our histopathological evaluations indicated significant
Acta Cir. Bras.. Publicado em: 2018-04
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4. Natural membranes of Hevea brasiliensis latex as delivery system for Casearia sylvestris leaf components
ABSTRACT Natural latex from Hevea brasiliensis (Wild. ex A.Juss) Müll.Arg., Euphorbiaceae, showed angiogenic action and Casearia sylvestris Sw., Salicaceae, leaf derivatives presented anti-inflammatory and wound healing activities. Therefore, an association of these effects was interesting for wound healing applications. The aims of this study were the deve
Rev. bras. farmacogn.. Publicado em: 2018-01
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5. AVALIACAO DA SAUDE CARDIOVASCULAR E DE QUALIDADE DE VIDA EM IDOSOS DE FORTALEZA-CEARA / Assessment of cardiovascular health and quality of life in elderly individuals in Fortaleza-Ceara.
Cardiovascular diseases, so common in elderly people with hypertension an important health risk, call for the adoption of preventive measures and drug therapies and nonpharmacological. The objective was to examine the relationship between cardiovascular health and quality of life of elderly hypertensive patients in Fortaleza, Ceara. The study was a descripti
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/02/2010
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6. Historical and epidemiological reflections about the epidemiologic foundations of contemporary Clinical Medicine / Reflexão histórico-epistemológica sobre os fundamentos epidemiológicos da Clínica Médica contemporânea
Since 1960 Clinical Medicine suffered a kind of inflection in its internal mechanisms of producing theoretical knowledge, as well as in the way that this knowledge is applied in practical life. The most important difference in relation to the past was that problems of clinical nature like, differential diagnosis, therapeutical decisions, and prognosis estima
Publicado em: 2010
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7. Microesferas lipídicas encapsuladas com proteínas antigênicas da membrana de Leishmania amazonensis com potencial aplicação terapêutica / Lipid microspheres loaded with antigenic membrane proteins of the Leishmania amazonensis as a potential therapeutical Application.
Microesferas lipídicas (ML) são excelentes sistemas de delivery de drogas e são relativamente estáveis. O Objetivo deste trabalho foi desenvolver um sistema capaz de encapsular proteínas antigênicas da membrana de L. amazonensis. Proteínas de membrana são importantes na formulação de vacinas, uma vez que estas proteínas são os primeiros component
Publicado em: 2009
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8. Avaliação da eficácia da Terapia Fotodinâmica mediada pela alumínio cloro ftalocianina - AlPHCl - lipossomal no tratamento de células derivadas do câncer bucal e sua atuação na regulação da via de sinalização PI3K/AKT/mTOR
Photodynamic Therapy (PDT) presents great potential for oral cancer treatment. PDT is known as a local therapy that not only destroy the primary tumor, but also trigger the immune system to recognize, to track down and to destroy remaining tumor cells. PDT can be defined as the administration of a nontoxic drug or dye known as a PS to a patient bearing a les
Publicado em: 2009
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9. Estudo dos efeitos biológicos de uma desintegrina recombinante do veneno da serpente Bothrops alternatus, DisBa-01, sobre a musculatura da parede abdominal após indução de hérnia incisional em ratos
INTRODUCTION: The incisional hernia (IH) is one of the most frequent complications after laparotomy, causing high rates of re-operations. Advances in suture material, in the guidelines for incisions, in the techniques of closure and use of dentures (screens), have failed in the elimination of this surgical complication. In this context, advances in the under
Publicado em: 2009
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10. The psychologization of psychoanalysis in education: a study of the connection of psychoanalysis and education in São Paulo Brazil / A psicologização da psicanálise na educação: um estudo da conexão psicanálise e educação em São Paulo - Brasil
After verifying a strong incidence of the psychologisation of education in a pool of municipal schools, we aimed to understand how psychoanalysis participated in this process. We started with the observation that once psychoanalysis has been picked over, it has turned a psychological knowledge with adaptative and normative purposes and, hence, one more theor
Publicado em: 2009
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11. Imagetherapy as a complementar therapeutical resource in Hashimotos thyroiditis: a bibliografic study / As terapias de imagens mentais como recurso terapêutico complementar na tireoidite de Hashimoto: um estudo bibliográfico
This research focused a bibliographic study of Imagetherapy as a therapeutic proposal to broach Hashimoto s disease. It has a start point in the results of a empirical noticed in the researcher clinical atuation, using directed imagination in a intention to low laboratorial score of auto--antibodies standed in auto-immune thyroiditis. This research has been
Publicado em: 2008
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12. Avaliação da resposta clínica e imunológica local de pacientes com neoplasia intra-epitelial cervical graus II e III tratadas com interferon alfa-2b intralesional.
Introduction: HPV is a DNA virus of tape double which can infect the lower genital tract. Its persistence, especially with oncogenic types is highly associated with the development of the high-grade squamous intraepithelial lesions. Treatment of these lesions is usually excisional (cold conization, laser conization, diathermic conization) and some studies ha
Publicado em: 2008