Threshold Dose Distribution
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Histological changes secondary to use of anti-angiogenic therapy after interruption of vasa vasorum flow in the descending aorta: results in a porcine model
Resumo Contexto Agentes antiangiogênicos podem ter implicações terapêuticas na progressão e manifestação da aterosclerose. Objetivos Demonstrar a alteração histológica secundária ao uso de bevacizumabe na aorta descendente de suínos submetida à interrupção dos vasa vasorum. Métodos Em doze suínos, divididos em dois grupos, foi realizada d
J. vasc. bras.. Publicado em: 25/04/2019
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2. Biological X-ray irradiator characterization for use with small animals and cells
This study presents the characterization of an X-ray irradiator through dosimetric tests, which confirms the actual dose rate that small animals and cells will be exposed to during radiobiological experiments. We evaluated the linearity, consistency, repeatability, and dose distribution in the positions in which the animals or cells are placed during irradia
Braz J Med Biol Res. Publicado em: 02/03/2017
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3. Modelo matemático de distribuição larga de dose limiar em tumores submetidos a múltiplas sessões de terapia fotodinâmica / Mathematical model for broad distribution of threshold dose in tumors treated with multiple photodynamic therapy sessions
Photodynamic therapy is a well known treatment option for many types of malignant and nonmalignant lesions. This technique causes cell damage through a photochemical reaction, generating oxidative agents responsible for tumor cell killing. In several cases, multiple PDT-sessions are needed to promote cancer eradication. However, several clinical studies have
Publicado em: 2010
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4. Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: Selective actions via GalR1 and GalR2 receptors
Galanin is a 29-aa neuropeptide with a complex role in pain processing. Several galanin receptor subtypes are present in dorsal root ganglia and spinal cord with a differential distribution. Here, we describe a generation of a specific galanin R2 (GalR2) agonist, AR-M1896, and its application in studies of a rat neuropathic pain model (Bennett). The res
National Academy of Sciences.
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5. Mill effect and dose-response relationships in byssinosis.
Four hundred and eighty-six textile workers in three cotton mills and one wool/synthetic mill were studied for symptoms and functional effects of workroom exposure to dust. Byssinosis was found in 5.7% of 386 cotton workers, with an apparent threshold level of 0.5 mg cotton dust/m3 of air. Mean post-shift functional declines were greater in workers exposed t
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6. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
Metal nanoshells are a class of nanoparticles with tunable optical resonances. In this article, an application of this technology to thermal ablative therapy for cancer is described. By tuning the nanoshells to strongly absorb light in the near infrared, where optical transmission through tissue is optimal, a distribution of nanoshells at depth in tissue can
National Academy of Sciences.
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7. Puma Lentivirus Is Controlled in Domestic Cats after Mucosal Exposure in the Absence of Conventional Indicators of Immunity
A high percentage of free-ranging pumas (Felis concolor) are infected with feline lentiviruses (puma lentivirus, feline immunodeficiency virus Pco [FIV-Pco], referred to here as PLV) without evidence of disease. PLV establishes productive infection in domestic cats following parenteral exposure but, in contrast to domestic cat FIV, it does not cause T-cell d
American Society for Microbiology.
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8. Dependence of junctional conductance on proton, calcium and magnesium ions in cardiac paired cells of guinea-pig.
1. The dependence of gap junctional conductance on the intracellular concentrations of H+, Ca2+ and Mg2+ was studied in paired myocytes dissociated enzymatically from guinea-pig ventricle. To apply an internal solution buffered to specific H+, Ca2+ or Mg2+ concentration directly to one aspect of the gap junction, the non-junctional membrane of one of the pai