Thyromimetics
Mostrando 1-2 de 2 artigos, teses e dissertações.
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1. Structural studies of the thyroid receptor (TR) and homology modeling of the thyroxine binding globulin (TBG) / Estudos estruturais do receptor do hormônio tireoidiano (hTR) e modelagem por homologia da globulina de ligação à tiroxina (TBG)
The thyroid hormones are involved in various regulatory effects, on diverse organs. Their fluctuations on the body are related to clinical scenarios of great relevance. This work deals with the study of two proteins which are directly related to the regulatory system associated to these hormones. The first one is the thyroxine-binding globulin (TBG), respons
Publicado em: 2005
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2. The thyromimetic T-0681 protects from atherosclerosis
This report describes studies in hyperlipidemic New Zealand White (NZW) rabbits investigating the impact of the liver-selective thyromimetic T-0681 on lipoprotein metabolism and the development of atherosclerosis. Prolonged treatment with T-0681 increased the hepatic expression of both LDL receptor and scavenger receptor class B, type I without affecting cho
American Society for Biochemistry and Molecular Biology.