Toxicogenetic
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Cardanol: toxicogenetic assessment and its effects when combined with cyclophosphamide
Abstract Cardanol is an effective antioxidant and is a compound with antimutagenic and antitumoral activity. Here, we evaluated the genotoxic and mutagenic potential of saturated side chain cardanol and its effects in combination with cyclophosphamide in preventing DNA damage, apoptosis, and immunomodulation. Swiss mice were treated with cardanol (2.5, 5 and
Genet. Mol. Biol.. Publicado em: 2016-06
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2. EFEITO TOXICOGENÉTICO DO POLIMORFISMO ALA16VAL DO GENE MnSOD EM LEUCÓCITOS EXPOSTOS IN VITRO AO METIL MERCÚRIO / TOXIGENETIC EFFECT OF ALA16VAL MnSOD GENE POLYMORPHISM ON LEUCOCYTES IN VITRO EXPOSED TO METHYL MERCURY
The environmental contamination by methyl mercury (MeHg) is a great health public problem in some world regions like Amazonia. The MeHg toxic effects seem to be influenced by environmental and genetic factors. However, there are few studies evaluating the genetic influence on MeHg toxicity in humans. Therefore, the aim of this present study was to evaluate t
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/03/2012
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3. Interação toxicogenética de polimorfismos da metaloproteinase-9 (MMP-9) da matriz extracelular e exposição ao mercúrio : efeitos sobre a atividade plasmática da MMP-9 / Toxicogenetic relevance of MMP-9 polymorphisms in mercury exposed subjects
A exposição ao mercúrio (Hg) causa efeitos deletérios à saúde, incluindo doenças cardiovasculares. Embora os mecanismos não estejam precisamente definidos, metaloproteinases (MMPs) -2 e -9 podem estar envolvidas. Expressão e atividades aumentadas destas MMPs são demonstradas em diversas condições patológicas, e estudos demonstraram que os nívei
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/07/2010
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4. Haplotypes of vitamin D modulate the circulate levels of leaf in exposed subjects / Modulação toxicogenetica das concentrações sanguineas e plasmaticas de chumbo por haplotipos do receptor da vitamina D
The Vitamin D Receptor (VDR) plays an important role in the toxicity of lead (Pb). Genetic factors, i.e polymorphisms, influence blood lead (Pb-B) concentrations in lead exposed subjects. However, only a few research studies have evaluated the effect of VDR polymorphism on the lead concentration in environmentally. Also, no studies have evaluated the combina
Publicado em: 2009