Toxicological Analysis
Mostrando 1-12 de 74 artigos, teses e dissertações.
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1. ANALYSIS OF BENZODIAZEPINES IN PLASMA SAMPLES BY DLLME AND LC-DAD: CRITICAL ASPECTS, FLAWS AND ISSUES ENCOUNTERED - A DISCUSSION
Dispersive liquid-liquid microextraction (DLLME) is a fast and simple technique and applicable procedure for the analysis of xenobiotics in different biological matrices. We have developed a DLLME method for the determination of benzodiazepines in plasma samples using liquid chromatography-diode-array detection (LC-DAD). During method validation, relative st
Química Nova. Publicado em: 2022
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2. Environmental effects of leachate extracts from reclaimed asphalt pavement: determination of metals, polycyclic aromatic hydrocarbon and acute toxicity to Daphnia magna
RESUMO Reclaimed Asphalt Pavement (RAP) has a variety of organic and inorganic compounds that can interact with the environment and promote deleterious effects on human health. This study investigated the potential toxicity of RAP through metal determination, polycyclic aromatic hydrocarbon (PAH) analysis and acute toxicity tests with Daphnia magna. Leached
Engenharia Sanitaria e Ambiental. Publicado em: 2022
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3. SIMPLE AND FAST DETERMINATION FOR GAMMA-HYDROXYBUTYRATE (GHB) IN URINE SAMPLE BY LLE AND GC-MS
Gamma-hydroxybutyrate (GHB) is a depressant of the central nervous system able to promote disinhibition, anterograde amnesia and its use is related to Drug-Facilitated Crimes (DFC). Urine is the biological matrix of choice for toxicological analysis in victims of rape and/or theft in suspected victims of DFC. The aim of this work was the development of a sim
Quím. Nova. Publicado em: 2021-02
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4. Evaluation and Geostatistical Study of Toxicological Risk by Water Ingestion with Al, Ba, Fe and Pb in Communities Close to Industrial Areas in the Brazilian Amazon
This study provides a risk assessment and risk maps related to the consumption of water contaminated by Al, Ba, Fe and Pb in an industrial area in the Brazilian Amazon. A total of 120 samples of drinking water were collected from 26 locations in the municipality of Barcarena, Pará State. Multiple elements were analyzed by inductively coupled plasma optical
J. Braz. Chem. Soc.. Publicado em: 2020-07
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5. Chemical characterization and toxicological assessment of hydroethanolic extract of Mandevilla velame xylopodium
Abstract The present study was aimed to characterize the chemical profile and evaluate the cytotoxicity and sub-chronic toxicity of the hydroethanolic extract of the xylopodium Mandevilla velame (A.St.-Hil.) Pichon, Apocynaceae. Chemical profile was analyzed by high performance liquid chromatography. Cytotoxic potential of hydroethanolic extract of the xylop
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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6. Toxicity and phytochemistry of eight species used in the traditional medicine of sul-mato-grossense, Brazil
Resumo O Cerrado brasileiro possui diversas espécies botânicas com fins medicinais utilizadas por comunidades tradicionais e muitas dessas plantas não estão incluídas na lista do Programa de Pesquisa de Plantas Medicinais da Central de Medicamentos. O objetivo deste estudo foi a triagem fitoquímica e o bioensaio toxicológico frente ao Brine shrimp L.
Braz. J. Biol.. Publicado em: 21/10/2019
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7. Outbreaks of nutritional cardiomyopathy in pigs in Brazil
RESUMO: Cardiomiopatia dilatada (CMD) é uma condição que afeta o miocárdio, raramente relatada em porcos. A DCM é caracterizada por dilatação ventricular, que resulta em disfunção sistólica e disfunção diastólica secundária e pode levar a arritmias e insuficiência cardíaca congestiva fatal. Este estudo descreve os achados clínicos, patológi
Pesq. Vet. Bras.. Publicado em: 13/10/2019
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8. Brazilian stingless bee propolis and geopropolis: promising sources of biologically active compounds
ABSTRACT Stingless bee products such as honey, pollen, propolis, and geopropolis have been used for centuries in traditional medicine for the treatment of several illnesses. Investigation of the biological activity of stingless bee products, especially propolis and geopropolis, has revealed promising therapeutic properties. About 20% of total Neotropical sti
Rev. bras. farmacogn.. Publicado em: 26/08/2019
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9. Changes in physicochemical and toxicological parameters of waters of Trincheira's River caused by road construction
Resumo Infraestruturas rodoviárias podem afetar áreas naturais com grande intensidade. Um trevo e uma trincheira foram construídas na cidade de Francisco Beltrão-Paraná-Brasil sobre um corpo d'água chamado Rio da Trincheira. O objetivo do presente estudo foi avaliar a qualidade de suas águas, em termos físico-químicos e toxicológicos, em quatro pon
Rev. Ambient. Água. Publicado em: 18/07/2019
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10. Análise do perfil e da tendência dos eventos toxicológicos ocorridos em crianças atendidas por um Hospital Universitário
Resumo Introdução Intoxicação humana é um importante problema de saúde pública, com elevado impacto socioeconômico e de saúde. Objetivo Determinar perfil e tendência dos eventos toxicológicos ocorridos em crianças. Método Estudo de tendência, realizado em crianças (menores de 12 anos, conforme Estatuto da Criança e do Adolescente) notif
Cad. saúde colet.. Publicado em: 2019-03
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11. Transgênicos e o princípio de equivalência substancial
RESUMO Objetivamos discutir os principais argumentos que estão envolvidos no debate sobre a cientificidade do Princípio de Equivalência Substancial (PES), que afirma serem os OGM quimicamente equivalentes aos organismos selecionados pelas técnicas tradicionais de melhoramento, não requerendo, portanto, estudos toxicológicos adicionais. Problematizamos
Estud. av.. Publicado em: 2019-01
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12. Guideline values and human risk assessment for the presence of anti-inflammatory drugs remaining in drinking water after lab scale treatment
Abstract This study aimed to determine whether the anti-inflammatory drugs that are most commonly consumed in Brazil, including diclofenac, ketoprofen, naproxen, indomethacin, ibuprofen and acetaminophen, are present in drinking water and to derive guideline values to characterize the human risk. These pharmaceuticals were quantified in surface waters by LC-
Braz. J. Pharm. Sci.. Publicado em: 07/06/2018