Transcriptional Profile
Mostrando 1-12 de 227 artigos, teses e dissertações.
-
1. Alterations in the Transcriptional Profile of the Liver Tissue and the Therapeutic Effects of Propolis Extracts in Alcohol-induced Steatosis in Rats
Abstract Abstract: The hepatoprotective effects of the ethanolic extracts of propolis (EEP) on alcohol-induced liver steatosis were investigated in Wistar rats. Chronic alcoholic fatty liver was induced by administration of 52% alcohol to male Wistar rats at the dose of 1% body weight for 7 weeks. Then animals were simultaneously treated with 50% ethanol sol
An. Acad. Bras. Ciênc.. Publicado em: 12/08/2019
-
2. Molecular evolution and transcriptional profile of GH3 and GH20 β-N-acetylglucosaminidases in the entomopathogenic fungus Metarhizium anisopliae
Abstract Cell walls are involved in manifold aspects of fungi maintenance. For several fungi, chitin synthesis, degradation and recycling are essential processes required for cell wall biogenesis; notably, the activity of β-N-acetylglucosaminidases (NAGases) must be present for chitin utilization. For entomopathogenic fungi, such as Metarhizium anisopliae,
Genet. Mol. Biol.. Publicado em: 10/12/2018
-
3. Gain of function in Mycobacterium bovis BCG Moreau due to loss of a transcriptional repressor
The Bacille Calmette-Guérin (BCG) vaccine comprises a family of genetically different strains derived by the loss of genomic regions (RDs) and other mutations. In BCG Moreau, loss of RD16 inactivates rv3405c * , encoding a transcriptional repressor that negatively regulates the expression of Rv3406, an alkyl sulfatase. To evaluate the impact of this loss o
Mem. Inst. Oswaldo Cruz. Publicado em: 11/10/2018
-
4. Aqueous extract of Baccharis trimera improves redox status and decreases the severity of alcoholic hepatotoxicity
ABSTRACT The metabolism of ethanol occurs mainly in the liver, promoting increase of reactive oxygen species and nitrogen, leading to redox imbalance. Therefore, antioxidants can be seen as an alternative to reestablish the oxidizing/reducing equilibrium. The aim of this study was to evaluate the antioxidant and hepatoprotective effect of aqueous extract of
Rev. bras. farmacogn.. Publicado em: 2017-12
-
5. Molecular Characterization of a MYB Protein from Oryza sativa for its Role in Abiotic Stress Tolerance
ABSTRACT The MYB family represents one of the most abundant classes of transcriptional regulators that perform pivotal role under different developmental processes and abiotic stresses. In present study, a MYB gene from Oryza sativa was selected for functional characterization. Bioinformatics analysis revealed that OsMYB1 cDNA encodes R2-R3 type DNA binding
Braz. arch. biol. technol.. Publicado em: 22/06/2017
-
6. Role of microRNAs in the treatment of type 2 diabetes mellitus with Roux-en-Y gastric bypass
The aim of this study was to investigate the effect of Roux-en-Y gastric bypass (RYGB) on the peripheral blood microRNAs (miRNAs) of patients with type 2 diabetes mellitus (T2DM). miRNAs are small 20- to 22-nucleotide (nt) noncoding RNAs. They constitute a novel class of gene regulators that negatively regulate gene expression at the post-transcriptional lev
Braz J Med Biol Res. Publicado em: 02/03/2017
-
7. Follicular helper T cell in immunity and autoimmunity
The traditional concept that effector T helper (Th) responses are mediated by Th1/Th2 cell subtypes has been broadened by the recent demonstration of two new effector T helper cells, the IL-17 producing cells (Th17) and the follicular helper T cells (Tfh). These new subsets have many features in common, such as the ability to produce IL-21 and to express the
Braz J Med Biol Res. Publicado em: 19/04/2016
-
8. Galactinol synthase transcriptional profile in two genotypes of Coffea canephora with contrasting tolerance to drought
Increased synthesis of galactinol and raffinose family oligosaccharides (RFOs) has been reported in vegetative tissues in response to a range of abiotic stresses. In this work, we evaluated the transcriptional profile of a Coffea canephora galactinol synthase gene (CcGolS1) in two clones that differed in tolerance to water deficit in order to assess the cont
Genet. Mol. Biol.. Publicado em: 2015-06
-
9. Transcriptional profile of fibroblasts obtained from the primary site, lymph node and bone marrow of breast cancer patients
Cancer-associated fibroblasts (CAF) influence tumor development at primary as well as in metastatic sites, but there have been no direct comparisons of the transcriptional profiles of stromal cells from different tumor sites. In this study, we used customized cDNA microarrays to compare the gene expression profile of stromal cells from primary tumor (CAF, n
Genet. Mol. Biol.. Publicado em: 2014-09
-
10. Ethylene response factors gene regulation and expression profiles under different stresses in rice
Stresses can cause large yield reductions in cultivated plants. The response to these stresses occurs via a plethora of signalling pathways, where a large number of genes is induced or repressed. Among the environmental stress responsive genes, there are the members of the ethylene response factors (ERF) gene family. The mRNA levels of different ERF are regu
Theor. Exp. Plant Physiol.. Publicado em: 2013-12
-
11. Expression profile of a Laccase2 encoding gene during the metamorphic molt in Apis mellifera (Hymenoptera,Apidae)
Expression profile of a Laccase2 encoding gene during the metamorphic molt in Apis mellifera (Hymenoptera, Apidae). Metamorphosis in holometabolous insects occurs through two subsequent molting cycles: pupation (metamorphic molt) and adult differentiation (imaginal molt). The imaginal molt in Apis mellifera L. was recently investigated in both histological a
Rev. Bras. entomol.. Publicado em: 31/05/2013
-
12. Estabelecimento de um patossistema modelo e análise da interação molecular planta-patógeno entre Eucalyptus grandis e Puccinia psidii Winter por meio da técnica de RNA-Seq. / Establishment of a model pathosystem and analysis of the molecular plant-pathogen interaction between Eucalyptus grandis and Puccinia psidii Winter
More than 20 million hectares are destined to Eucalyptus plantations worldwide and Brazil has the second largest planted area. The International Eucalyptus Genome Network, EUCAGEN, was created in 2007 in order to perform genomic research on Eucalyptus. Brazil provided the biological material from the model tree (Brasuz) to have the complete genome sequenced
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/05/2012