Transcriptomics
Mostrando 1-12 de 19 artigos, teses e dissertações.
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1. Metabolomics applied to maternal and perinatal health: a review of new frontiers with a translation potential
The prediction or early diagnosis of maternal complications is challenging mostly because the main conditions, such as preeclampsia, preterm birth, fetal growth restriction, and gestational diabetes mellitus, are complex syndromes with multiple underlying mechanisms related to their occurrence. Limited advances in maternal and perinatal health in recent deca
Clinics. Publicado em: 21/03/2019
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2. Genome-wide transcription analyses in Mycobacterium tuberculosis treated with lupulone
Mycobacterium tuberculosis (M. tuberculosis), the causative agent of tuberculosis, still causes higher mortality than any other bacterial pathogen until now. With the emergence and spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR-TB) strains, it becomes more important to search for alternative targets to develop new antimycobacterial d
Braz. J. Microbiol.. Publicado em: 18/04/2014
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3. Estabelecimento de um patossistema modelo e análise da interação molecular planta-patógeno entre Eucalyptus grandis e Puccinia psidii Winter por meio da técnica de RNA-Seq. / Establishment of a model pathosystem and analysis of the molecular plant-pathogen interaction between Eucalyptus grandis and Puccinia psidii Winter
More than 20 million hectares are destined to Eucalyptus plantations worldwide and Brazil has the second largest planted area. The International Eucalyptus Genome Network, EUCAGEN, was created in 2007 in order to perform genomic research on Eucalyptus. Brazil provided the biological material from the model tree (Brasuz) to have the complete genome sequenced
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/05/2012
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4. Proteômica e transcriptômica aplicadas ao estudo da variabilidade do veneno de Bothrops jararaca (serpentes:viperidae) / Proteomics and transcriptomics applied to the study of Bothrops jararaca venom variability (Serpentes: Viperidae)
Estudos prévios demonstraram que as atividades biológicas do veneno da serpente Bothrops jararaca sofrem significantes modificações ontogenéticas. Neste estudo é apresentada uma análise comparativa do proteoma, peptidoma e transcriptoma da glândula de veneno de filhotes e adultos de B. jararaca, correlacionando os resultados obtidos com algumas carac
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/05/2011
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5. Survey of transcripts expressed by the invasive juvenile stage of the liver fluke Fasciola hepatica
Background: The common liver fluke Fasciola hepatica is the agent of a zoonosis with significant economic consequences in livestock production worldwide, and increasing relevance to human health in developing countries. Although flukicidal drugs are available, re-infection and emerging resistance are demanding new efficient and inexpensive control strategies
Publicado em: 2011
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6. Comparative analysis of clustering methods for gene expression data
Large scale approaches, namely proteomics and transcriptomics, will play the most important role of the so-called post-genomics. These approaches allow experiments to measure the expression of thousands of genes from a cell in distinct time points. The analysis of this data can allow the the understanding of gene function and gene regulatory networks (Eisen
Publicado em: 2003
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7. Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana
Plant metabolism is a complex set of processes that produce a wide diversity of foods, woods, and medicines. With the genome sequences of Arabidopsis and rice in hands, postgenomics studies integrating all “omics” sciences can depict precise pictures of a whole-cellular process. Here, we present, to our knowledge, the first report of investigation for ge
National Academy of Sciences.
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8. Transcriptome and Proteome Analysis of Bacillus subtilis Gene Expression Modulated by Amino Acid Availability
A comprehensive study of Bacillus subtilis gene expression patterns in response to amino acid availability was performed by means of proteomics and transcriptomics. The methods of two-dimensional protein gel electrophoresis and DNA macroarray technology were combined to analyze cells exponentially grown in minimal medium with and without 0.2% Casamino Acids
American Society for Microbiology.
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9. NASCArrays: a repository for microarray data generated by NASC’s transcriptomics service
NASC operates an Affymetrix ‘GeneChip’ (microarray) service for the Arabidopsis thaliana community. All data produced by the service are publicly available through our microarray data base ‘NASCArrays’ published at http://affymetrix.arabidopsis.info. The data are accessible through text searching and a series of data mining tools. All data are annota
Oxford University Press.
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10. An Integrated Transcriptomics and Proteomics Analysis of the Secretome of the Helminth Pathogen Fasciola hepatica: PROTEINS ASSOCIATED WITH INVASION AND INFECTION OF THE MAMMALIAN HOST*
To infect their mammalian hosts, Fasciola hepatica larvae must penetrate and traverse the intestinal wall of the duodenum, move through the peritoneum, and penetrate the liver. After migrating through and feeding on the liver, causing extensive tissue damage, the parasites move to their final niche in the bile ducts where they mature and produce eggs. Here w
The American Society for Biochemistry and Molecular Biology.
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11. Cellular stress created by intermediary metabolite imbalances
Small molecules generally activate or inhibit gene transcription as externally added substrates or as internally accumulated end-products, respectively. Rarely has a connection been made that links an intracellular intermediary metabolite as a signal of gene expression. We report that a perturbation in the critical step of a metabolic pathway—the D-galacto
National Academy of Sciences.
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12. Genomic Studies with Escherichia coli MelR Protein: Applications of Chromatin Immunoprecipitation and Microarrays
Escherichia coli MelR protein is a transcription activator that is essential for melibiose-dependent expression of the melAB genes. We have used chromatin immunoprecipitation to study the binding of MelR and RNA polymerase to the melAB promoter in vivo. Our results show that MelR is associated with promoter DNA, both in the absence and presence of the induce
American Society for Microbiology.