Transformed Cells
Mostrando 1-12 de 5016 artigos, teses e dissertações.
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1. Rapamycin and Paclitaxel Affect Human Aortic Smooth Muscle Cells-Derived Foam Cells Viability and Proliferation
Abstract Introduction: Drug-eluting stents (DES) coated with rapamycin or paclitaxel as antiproliferative substances significantly reduced the incidence of clinical restenosis and had fewer side effects after percutaneous coronary intervention. However, DES coated with rapamycin or paclitaxel still cause restenosis due to abnormal tissue growth which remain
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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2. Growth hormone in the tumor microenvironment
ABSTRACT Tumor development is a multistep process whereby local mechanisms enable somatic mutations during preneoplastic stages. Once a tumor develops, it becomes a complex organ composed of multiple cell types. Interactions between malignant and non-transformed cells and tissues create a tumor microenvironment (TME) comprising epithelial cancer cells, cance
Arch. Endocrinol. Metab.. Publicado em: 10/01/2020
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3. Immunohistochemical localization of progesterone receptors alpha (PRA) in ovary of the pseudopregnant rabbit
Abstract Progesterone plays an important role in the reproductive function and follicular development in mammals. The aim of the present study was to examine the localization of progesterone receptor alpha (PRA) in ovary of pseudopregnant rabbit by immunohistochemical methods. Samples were collected from 14 h. to 18 days of pseudopregnancy. At the first stag
Anim. Reprod.. Publicado em: 25/11/2019
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4. Photovoltaic Cell Temperature Estimation for a Grid-Connect Photovoltaic Systems in Curitiba
Abstract The photovoltaic solar energy has been growing in installed capacity worldwide year by year, and Brazil has also been investing in this renewable source of energy generation. The conversion of light into electrical energy occurs in the photovoltaic cells, which are sensitive to the increase of the temperature. A considerable amount of the energy in
Braz. arch. biol. technol.. Publicado em: 25/11/2019
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5. Estabelecimento de sistema bacteriano de expressão de peptídeos derivados da enzima vegetal RuBisCO
Resumo O objetivo do presente estudo foi estabelecer um sistema bacteriano de expressão de peptídeos derivados da proteólise simulada in silico da enzima ribulose-1,5-bisfosfato carboxilase oxigenase (RuBisCO), proveniente de soja, visando viabilizar um método sustentável de produção dessas moléculas para futura aplicação industrial. Inicialmente,
Braz. J. Food Technol.. Publicado em: 01/08/2019
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6. Human papillomavirus and genome instability: from productive infection to cancer
Infection with high oncogenic risk human papillomavirus types is the etiological factor of cervical cancer and a major cause of other epithelial malignancies, including vulvar, vaginal, anal, penile and head and neck carcinomas. These agents affect epithelial homeostasis through the expression of specific proteins that deregulate important cellular signaling
Clinics. Publicado em: 06/09/2018
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7. Terpene Esters from Natural Products: Synthesis and Evaluation of Cytotoxic Activity
ABSTRACT Natural steroids and triterpenes such as b-sitosterol, stigmasterol, lupeol, ursolic and betulinic acids were transformed into its hexanoic and oleic esters, to evaluate the influence of chemical modification towards the cytotoxic activities against tumor cells. The derivatives were evaluated against five tumor cell lines [OVCAR-8 (ovarian carcinoma
An. Acad. Bras. Ciênc.. Publicado em: 14/08/2017
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8. Heterologous expression of a rice metallothionein isoform (OsMTI-1b) in Saccharomyces cerevisiae enhances cadmium, hydrogen peroxide and ethanol tolerance
Abstract Metallothioneins are a superfamily of low-molecular-weight, cysteine (Cys)-rich proteins that are believed to play important roles in protection against metal toxicity and oxidative stress. The main purpose of this study was to investigate the effect of heterologous expression of a rice metallothionein isoform (OsMTI-1b) on the tolerance of Saccharo
Braz. J. Microbiol.. Publicado em: 2017-07
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9. Molecular Characterization of a MYB Protein from Oryza sativa for its Role in Abiotic Stress Tolerance
ABSTRACT The MYB family represents one of the most abundant classes of transcriptional regulators that perform pivotal role under different developmental processes and abiotic stresses. In present study, a MYB gene from Oryza sativa was selected for functional characterization. Bioinformatics analysis revealed that OsMYB1 cDNA encodes R2-R3 type DNA binding
Braz. arch. biol. technol.. Publicado em: 22/06/2017
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10. The effect of magnesium on mitotic spindle formation in Schizosaccharomyces pombe
Abstract Magnesium (Mg2+), an essential ion for cells and biological systems, is involved in a variety of cellular processes, including the formation and breakdown of microtubules. The results of a previous investigation suggested that as cells grow the intracellular Mg2+ concentration falls, thereby stimulating formation of the mitotic spindle. In the prese
Genet. Mol. Biol.. Publicado em: 07/07/2016
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11. Inflammatory response of Haemophilus influenzae biotype aegyptius causing Brazilian Purpuric Fever
The Brazilian Purpuric Fever (BPF) is a systemic disease with many clinical features of meningococcal sepsis and is usually preceded by purulent conjunctivitis. The illness is caused by Haemophilus influenza biogroup aegyptius, which was associated exclusively with conjunctivitis. In this work construction of the las gene, hypothetically responsible for this
Braz. J. Microbiol.. Publicado em: 2014-12
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12. Re-Ingeniería de apatita natural para soporte de tejidos óseos
Recent progresses in orthopedic medicine, traumatology and odontology have created a great requirement for biomaterials, especially those products having a composition based on calcium orthophosphate, which is similar to inorganic bone structure. Given this situation, there has been an intense search for new origins and resources of biomaterials. The natural
Matéria (Rio J.). Publicado em: 2014-09