Transgenic Mosquitoes
Mostrando 1-12 de 17 artigos, teses e dissertações.
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1. Reaction-diffusion Model Applied to the Population Dynamics of Wild and Transgenic Mosquitoes
RESUMO Devido aos progressos recentes na manipulação genética, os mosquitos transgênicos podem ser uma alternativa viável para reduzir algumas doenças. Condições de viabilidade são obtidas pela simulação e análise de modelos matemáticos que descrevem o comportamento de populações de mosquitos selvagens e transgênicos convivendo em uma mesma �
TEMA (São Carlos). Publicado em: 2020-12
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2. Estudo de dispersão de machos da linhagem transgênica OX513A de Aedes aegypti. / Dispersal study with transgenic males line OX513A of Aedes aegypti.
Novas alternativas são necessárias para controlar o mosquito transmissor da dengue, como a manipulação genética. Baseada na técnica do inseto estéril (SIT) que compreende a esterilização, a criação em massa e a liberação de grandes números de insetos machos estéreis em uma área alvo, a tecnologia RIDL, baseada em SIT, compreende criação em
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/05/2012
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3. Análise da expressão de regiões da proteína Circumsporozoíta de Plasmodium sp. em Aedes aegypti infectado por Plasmodium gallinaceum. / Expression analyses of Plasmodium sp. Circumsporozoite protein regions in Plasmodium gallinaceum infected Aedes aegypti.
Transgenic mosquitoes that impair malaria transmission can be an alternative control but currently an effective line is not available. A better understanding of mosquito interaction with pathogens is very important to improve refractory transgene design. Circumsporozoite protein (CSP) has two conserved domains that could be involved in spz penetration into m
Publicado em: 2009
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4. Controle genético de mosquitos Culex quinquefasciatus / Genetic control of Culex quinquefasciatus mosquitoes
The Culex quinquefasciatus mosquitoes are considered urban plague and are able to grown in polluted water achieving high density. This specie are important vectors in the transmission of parasites and arbovirus. Chemical control methods shown to be ineffective and highly hazards to the environment. In this way, new technologies of control have been developed
Publicado em: 2008
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5. Perspectives in the control of infectious diseases by transgenic mosquitoes in the post-genomic era: a review
Arthropod-borne diseases caused by a variety of microorganisms such as dengue virus and malaria parasites afflict billions of people worldwide imposing major economic and social burdens. Despite many efforts, vaccines against diseases transmitted by mosquitoes, with the exception of yellow fever, are not available. Control of such infectious pathogens is mai
Memórias do Instituto Oswaldo Cruz. Publicado em: 10/04/2007
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6. Controle ótimo do vetor da malária para o modelo matemático sazonal / Optimal control for malaria vector for a seasonal mathematical model
In the Amazonian region occurs a variation in the malaria incidence, which is related to the pluviometric variation annual. The mathematical model proposed here considers this seasonality and different treatment intensities accessible to the infected people. The numerical evidence the seasonal fluctuation and the relationship between the environment temperat
Publicado em: 2007
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7. Germline transformation of Aedes fluviatilis (Diptera:Culicidae) with the piggyBac transposable element
The technique to generate transgenic mosquitoes requires adaptation for each target species because of aspects related to species biology, sensitivity to manipulation and rearing conditions. Here we tested different parameters on the microinjection procedure in order to obtain a transgenic Neotropical mosquito species. By using a transposon-based strategy we
Memórias do Instituto Oswaldo Cruz. Publicado em: 2006-11
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8. Assessing fitness costs for transgenic Aedes aegypti expressing the GFP marker and transposase genes
The development of transgenic mosquitoes that are refractory to the transmission of human diseases such as malaria, dengue, and yellow fever has received much interest due to the ability to transform a number of vector mosquito species with transposable elements. Transgenic strains of mosquitoes have been generated with molecular techniques that exhibit a re
National Academy of Sciences.
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9. Transgenic alteration of Toll immune pathway in the female mosquito Aedes aegypti
Reverse genetics is a powerful tool for understanding gene functions and their interactions in the mosquito innate immunity. We took the transgenic approach, in combination with the RNA interference (RNAi) technique, to elucidate the role of mosquito REL1, a homolog of Drosophila Dorsal, in regulation of Toll immune pathway in the mosquito Aedes aegypti. By
National Academy of Sciences.
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10. Engineering blood meal-activated systemic immunity in the yellow fever mosquito, Aedes aegypti
Progress in molecular genetics makes possible the development of alternative disease control strategies that target the competence of mosquitoes to transmit pathogens. We tested the regulatory region of the vitellogenin (Vg) gene of Aedes aegypti for its ability to express potential antipathogen factors in transgenic mosquitoes. Hermes-mediated transformatio
The National Academy of Sciences.
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11. Robust gut-specific gene expression in transgenic Aedes aegypti mosquitoes
Genetic modification of the vectorial capacity of mosquito vectors of human disease requires promoters capable of driving gene expression with appropriate tissue and stage specificity. We report on the characterization in transgenic Aedes aegypti of two mosquito gut-specific promoters. A 1.4-kb DNA fragment adjacent to the 5′ end of the coding region
The National Academy of Sciences.
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12. Inhibition of luciferase expression in transgenic Aedes aegypti mosquitoes by Sindbis virus expression of antisense luciferase RNA
A rapid and reproducible method of inhibiting the expression of specific genes in mosquitoes should further our understanding of gene function and may lead to the identification of mosquito genes that determine vector competence or are involved in pathogen transmission. We hypothesized that the virus expression system based on the mosquito-borne Alphavirus,
The National Academy of Sciences.