Tuberculosis Pleuritis
Mostrando 1-10 de 10 artigos, teses e dissertações.
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1. Application of the Polymerase Chain Reaction (PCR) for identification of the Mycobacterium tuberculosis in patients with suspicion pleural tuberculosis. / Aplicação da reação em Cadeia da Polimerase (PCR) para identificação do Mycobacterium tuberculosis em pacientes com suspeita de tuberculose pleural.
O presente estudo tem como principal objetivo o emprego da reação em cadeia da polimerase (PCR) na elucidação da etiologia dos derrames pleurais dos pacientes com suspeita de pleurite tuberculosa, comparando-o com as técnicas diagnósticas disponíveis na atualidade. O diagnóstico da tuberculose pleural costuma ser feito por meio dos dados clínicos e
Publicado em: 2001
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2. T-lymphocyte response in a guinea pig model of tuberculous pleuritis.
The ability to induce tuberculous pleuritis in Mycobacterium bovis BCG-vaccinated guinea pigs was investigated as a model of human disease. A pleural effusion of 5 to 10 ml was obtained 6 to 7 days after the bilateral pleural injection of a suspension of heat-killed M. tuberculosis cells. Histological lesions were indicative of granulomatous pleuritis. Compa
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3. Interleukin 12 at the site of disease in tuberculosis.
Interleukin 12 (IL-12), a heterodimeric cytokine composed of p40 and p35 chains, has potent immunologic effects in vitro. We used tuberculous pleuritis as a model to study the immunoregulatory potential of IL-12 in vivo at the site of human infectious disease. Messenger RNAs for p40 and p35 were detected in pleural fluid from six of six patients by reverse-t
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4. Quantitation in inflammatory pleural disease to distinguish tuberculous and paramalignant from chronic non-specific pleuritis.
AIM: To determine by morphometry if pleural biopsies with the histopathological diagnosis of "non-specific pleuritis", malignant, and tuberculous disease could be distinguished morphologically from those with truly non-specific disease. METHODS: Each pleural biopsy was reviewed taking into account three compartments of reference: the visceral/parietal mesoth
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5. Cytokine production at the site of disease in human tuberculosis.
Clinical and immunologic evidence suggests that tuberculous pleuritis provides a model to understand protective immune mechanisms against Mycobacterium tuberculosis. We therefore evaluated the pattern of cytokine mRNA expression and cytokine production in pleural fluid and blood of patients with tuberculous pleuritis. RNA was extracted from mononuclear cells
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6. Transpleural gradient of 1,25-dihydroxyvitamin D in tuberculous pleuritis.
We used tuberculous pleuritis as a model to study the compartmentalization and potential immunoregulatory role of 1,25-dihydroxyvitamin D [1,25-(OH)2-D] in human granulomatous disease. In tuberculous pleuritis, mean concentrations of total 1,25-(OH)2-D were elevated in pleural fluid, compared to blood (67 pg/ml vs. 35 pg/ml). Concentrations of albumin, prote
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7. Zinc, copper, and iron content of pleural fluid in benign and neoplastic disease
Zinc, copper, and iron were measured in the pleural fluid of 86 patients with benign conditions (including congestive heart failure, pulmonary embolus, collagen disease, pneumonitis, non-specific pleuritis, and tuberculosis) and in 116 patients with malignant disease (including lymphoma, breast carcinoma, primary lung cancer, and metastatic lung cancer). Tho
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8. Identification of a 35-kilodalton Mycobacterium tuberculosis protein containing B- and T-cell epitopes.
Screening of a Mycobacterium tuberculosis genomic DNA library in the lambda gt11 expression vector was carried out by using, as probes, sera from tuberculous patients and murine monoclonal antibody H61.3 recognizing a mycobacterial 35-kilodalton protein present only on the M. tuberculosis complex. The recombinant beta-galactosidase-fused protein present in t
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9. Infection of the pleura by Aspergillus fumigatus
Pleural aspergillosis occurs mostly in established cases of pleural empyema with a broncho-pleural fistula. Ten such patients are reported here: in all, Aspergillus fumigatus infection was related to tuberculosis. In three cases with an active, sputum-positive tuberculous process the pleural empyema was a complication of spontaneous pneumothorax in two, and
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10. Lymphocyte populations during tuberculosis infection: V beta repertoires.
The immune response to Mycobacterium tuberculosis is mediated by T lymphocytes. We studied the changes in lymphocyte populations occurring in peripheral blood, pleural fluid, and ascites during tuberculosis infection. For this purpose, we compared recent-onset patients (newly converted to positive Mantoux reactions) with previously diagnosed patients (indivi