Tumorigenic Cells
Mostrando 1-12 de 522 artigos, teses e dissertações.
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1. Tumorigenic and immunological roles of Heat shock protein A2 in pancreatic cancer: a bioinformatics analysis
SUMMARY OBJECTIVE: Heat shock protein A2 has been reported to be tightly associated with tumorigenesis and tumor progression. This study aimed to determine the oncogenic and immunological roles of Heat shock protein A2 in pancreatic cancer by bioinformatics. METHODS: Expression of Heat shock protein A2 in tumorous and normal specimens of pancreatic cancer
Revista da Associação Médica Brasileira. Publicado em: 2022
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2. “Half-Sandwich”/RuII Anticancer Complexes Containing Triphenylphosphine and p-Substituted Benzoic Acids
Mononuclear and binuclear RuII/arene/triphenylphosphine complexes with p-substituted benzoic acid derivatives were prepared and characterized. These monocationic complexes of type [Ru(η6-p-cymene)(PPh3)L] (L = benzoic acid (1), p-hydroxybenzoic acid (2), p-nitrobenzoic acid (3) and terephthalic acid (4)) were characterized using various techniques, such as
J. Braz. Chem. Soc.. Publicado em: 2020-11
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3. Platelet activating factor receptor antagonists improve the efficacy of experimental chemo- and radiotherapy
Platelet activating factor is a lipid mediator of inflammation, and in recent decades, it has emerged as an important factor in tumor outcomes. Platelet activating factor acts by specific binding to its receptor, which is present in both tumor cells and cells that infiltrate tumors. Pro-tumorigenic effects of platelet activating factor receptor in tumors inc
Clinics. Publicado em: 11/10/2018
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4. Antineoplastic potential of the aqueous crude extract of Eugenia uniflora L. in human cervical cancer
Abstract Considering the high prevalence of human cervical cancer and the adverse effects of the available treatments, it is important to develop studies involving plants. Eugenia uniflora L. is a Brazilian native plant widely used in folk medicine and some biological effects have already been described. In this study, we investigated the biologicals effects
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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5. A cytotoxic Petiveria alliacea dry extract induces ATP depletion and decreases β-F1-ATPase expression in breast cancer cells and promotes survival in tumor-bearing mice
Abstract Metabolic plasticity in cancer cells assures cell survival and cell proliferation under variable levels of oxygen and nutrients. Therefore, new anticancer treatments endeavor to target such plasticity by modifying main metabolic pathways as glycolysis or oxidative phosphorylation. In American traditional medicine Petiveria alliacea L., Phytolaccacea
Rev. bras. farmacogn.. Publicado em: 2017-06
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6. Valproic acid inhibits the invasion of PC3 prostate cancer cells by upregulating the metastasis suppressor protein NDRG1
Abstract Valproic acid (VPA) is a clinically available histone deacetylase inhibitor with promising anticancer attributes. Recent studies have demonstrated the anticancer effects of VPA on prostate cancer cells. However, little is known about the differential effects of VPA between metastatic and non-metastatic prostate cancer cells and the relationship betw
Genet. Mol. Biol.. Publicado em: 2015-12
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7. Behavior of the P1.HTR mastocytoma cell line implanted in the chorioallantoic membrane of chick embryos
The P1.HTR cell line includes highly transfectable cells derived from P815 mastocytoma cells originating from mouse breast tissue. Despite its widespread use in immunogenic studies, no data are available about the behavior of P1.HTR cells in the chick embryo chorioallantoic membrane model. The objective of the present investigation was to study the effects o
Braz J Med Biol Res. Publicado em: 11/01/2013
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8. Identification of alternative transcripts of rat CD9 expressed by tumorigenic neural cell lines and in normal tissues
CD9 is the best-studied member of the tetraspanin family of transmembrane proteins. It is involved in various fundamental cellular processes and its altered expression is a characteristic of malignant cells of different origins. Despite numerous investigations confirming its fundamental role, the heterogeneity of CD9 or other tetraspanin proteins was conside
Genet. Mol. Biol.. Publicado em: 2013
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9. Proteção por L-carnitina ou piracetam contra a morte celular causada por sinvastatina em celulas tumorais e não tumorais / Protection by L-carnitine or piracetam against cell death caused by simvastatin in tumor and non tumorigenic cell lines
Statins are drugs widely used in the treatment of hypercholesterolemia. They are competitive inhibitors of 3-hydroxy 3-methylglutaryl coenzyme A (HMG-CoA) reductase preventing in this way, the synthesis of cholesterol. L-carnitine is synthesized from the essential aminoacids lysine and methionine in liver and kidney and plays na important role in the cell, w
Publicado em: 2010
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10. FGF2 species of 18 and 22.5 kDa: paracrine molecular signaling and biological functions / FGF2 de 18kDa e de 22,5kDa: sinalização molecular parácrina e funções biológias
FGF2 (Fibroblast Growth Factor 2), the founder of the FGF family, has regulatory functions in mitogenesis, differentiation, morphogenesis and tissue repair. Multiple FGF2 molecular species, sharing a C-terminal sequence of 155 amino acids, are translated from different iniciation sites of the same mRNA. The smaller, the FGF2-18kD, is extracellularly released
Publicado em: 2010
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11. Avaliação do dano radioinduzido, capacidade de reparo e morte cecular em células humanas tumorais (T-47D e MCF-7) e não tumorais (MCF-10) de mama / Evaluation of the radioinduced damage, repair capacity and cell death on human tumorigenic (T-47D and MCF-7) and nontumorigenic (MCF-10) cell lines of breast
Breast cancer is one of the most common malignancies that account women, representing about one in three of all female neoplasm. Approximately, 90% of cases are considered sporadic, attributed to somatic events and about 10% have a family history and this only 4 - 5 % is decurrent of hereditary factors. In the clinic, ionizing radiation is a major tool utili
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/07/2008
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12. Análise de expressão gênica por microarrays de cDNA em linhagens de células adrenais tumorigênicas tratadas com FGF2 e ACTH / cDNA microarrays used in the analysis of the gene expression of tumorigenic adrenocortical lineages treated with FGF2 and ACTH
Nowadays, a molecular biology premise establishes the activation of transcription programs related to specific biological processes. At this work the objective is to describe regulated genes that, once clustered, are able to indicate the running programs when murine adrenocortical lineage Y1 is treated with fibroblast growth factor (FGF2) or by adrenocortico
Publicado em: 2006