Uliginosin B
Mostrando 1-5 de 5 artigos, teses e dissertações.
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1. Uliginosin B, a natural phloroglucinol derivative with antidepressant-like activity, increases Na+,K+-ATPase activity in mice cerebral cortex
ABSTRACT Uliginosin B, a phloroglucinol isolated from Hypericum polyanthemum Klotzsch ex Reichardt, Hypericaceae, has antidepressant-like effect in the forced swimming test in rodents and inhibits monoamines neuronal reuptake without binding to their neuronal carriers. Studies showed the involvement of Na+,K+-ATPase brain activity in depressive disorders, as
Rev. bras. farmacogn.. Publicado em: 2016-10
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2. G-protein activation revealed by [35S]-GTPγS binding assay is involved on the antidepressant-like effect of Hyperi cum caprifoliatum and Hypericum polyanthemumcyclohexane extracts
AbstractPrevious studies by us demonstrated the antidepressant-like and antinociceptive effects of lipophilic extracts and dimeric acyl-phloroglucinols from species of the genus Hypericum native to Southern Brazil. Uliginosin B and HC1 (an enriched phloroglucinol fraction from Hypericum caprifoliatum) are able to inhibit monoamine synaptosomal uptake without
Rev. bras. farmacogn.. Publicado em: 2015-08
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3. Antiproliferative activity of the hexanic extract and phloroglucinols from Hypericum brasiliense
Natural products are regarded as major and important sources of molecules used in chemotherapy. Hypericum brasiliense Choisy, Hypericaceae, is an annual bush, native in the southern and southeastern Brazil. This species has been used in Brazilian folk medicine the anti-spasmodic and for the treatment of infectious diseases. H. brasiliense is chemically compo
Rev. bras. farmacogn.. Publicado em: 2013-10
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4. Avaliação do mecanismo de ação antidepressiva e estudo da toxicidade oral aguda e de doses repetidas de hypericum polyanthemum em camundongos / Evaluation of the antidepressant mechanism of action and oral toxicity study of Hypericum polyanthemum in mice
O objetivo deste trabalho foi ampliar o estudo do mecanismo de ação antidepressivo de Hypericum polyanthemum (POL) e de seu composto derivado da classe dos floroglucinóis uliginosina B (ULI). Considerando o potencial desta planta para o desenvolvimento de novos fármacos, realizou-se um estudo pré-clínico de toxicidade aguda e doses repetidas de POL em
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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5. Atividade antibacteriana de floroglucinóis e do extrato hexânico de Hypericum brasiliense Choysi
Three phloroglucinols were obtained from Hypericum brasiliense: japonicine A (1), isouliginosin B (2) and uliginosin B (3). Bioautography and disk diffusion methods were used to determine antibacterial activity of the hexanic extract. Strains of the Coagulase Negative Staphylococcus and American Methicillin Resistant Staphylococcus aureus clones showed a gro
Química Nova. Publicado em: 2009