Umbilical Cord Transplantation
Mostrando 1-12 de 36 artigos, teses e dissertações.
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1. Haploidentical transplantation outcomes are comparable with those obtained with identical human leukocyte antigen allogeneic transplantation in Chilean patients with benign and malignant hemopathies
Abstract Introduction Patients with benign or malignant blood disorders, who require allogeneic stem cell transplantation and lack an identical human leukocyte antigen HLA identicalHL sibling donor, could be transplanted with hematopoietic stem cells from unrelated adult or umbilical cord donors. However, in our country, both approaches are costly and time-
Hematol., Transfus. Cell Ther.. Publicado em: 2020-03
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2. Spontaneous splenic rupture associated with multiple myeloma: a serious and unusual case
Abstract Introduction Patients with benign or malignant blood disorders, who require allogeneic stem cell transplantation and lack an identical human leukocyte antigen HLA identicalHL sibling donor, could be transplanted with hematopoietic stem cells from unrelated adult or umbilical cord donors. However, in our country, both approaches are costly and time-
Hematol., Transfus. Cell Ther.. Publicado em: 2020-03
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3. Assessing the impact of ABO incompatibility on major allogeneic hematopoietic stem cell transplant outcomes: a prospective, single-center, cohort study
Abstract Background ABO blood group incompatibility between donor and recipient is associated with a number of immunohematological complications, but is not considered a major contraindication to allogeneic hematopoietic stem cell transplantation. However, available evidence from the literature seems to be conflicting as to the impact of incompatibility on
Hematol., Transfus. Cell Ther.. Publicado em: 15/04/2019
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4. Hematopoietic Stem Cell Transplantation in Mucopolysaccharidosis Type II: A Literature Review and Critical Analysis
Abstract Mucopolysaccharidosis II (MPS II—Hunter syndrome) is an X-linked lysosomal storage disorder caused by a deficiency in iduronate-2 sulfatase. Enzyme replacement therapy does not cross the blood–brain barrier (BBB), limiting the results in neurological forms of the disease. Another treatment option for MPS, hematopoietic stem cell transplantation
J. inborn errors metab. screen.. Publicado em: 28/02/2019
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5. Outcomes of allogeneic hematopoietic stem cell transplantation for lymphomas: a single-institution experience
ABSTRACT Introduction: Allogeneic hematopoietic stem cell transplantation offers the opportunity for extended survival in patients with Hodgkin's and non-Hodgkin lymphomas who relapsed after, or were deemed ineligible for, autologous transplantation. This study reports the cumulative experience of a single center over the past 14 years aiming to define the
Rev. Bras. Hematol. Hemoter.. Publicado em: 2016-12
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6. Molecular characterization of microbial contaminants isolated from Umbilical Cord Blood Units for transplant
ABSTRACT Disposal of Umbilical Cord Blood Units due to microbial contamination is a major problem in Cord Blood Banks worldwide as it reduces the number of units available for transplantation. Additionally, economic losses are generated as result of resources and infrastructure used to obtain such units. Umbilical Cord Blood Units that showed initial microbi
Braz J Infect Dis. Publicado em: 2015-12
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7. Unrelated hematopoietic stem cell transplantation in the pediatric population: single institution experience
OBJECTIVE: Hematopoietic stem cell transplantation has been successfully used to treat the pediatric population with malignant and non-malignant hematological diseases. This paper reports the results up to 180 days after the procedure of all unrelated hematopoietic stem cell transplantations in pediatric patients that were performed in one institution.METHOD
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-08
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8. Transplantation of mononuclear cells from human umbilical cord blood promotes functional recovery after traumatic spinal cord injury in Wistar rats
Cell transplantation is a promising experimental treatment for spinal cord injury. The aim of the present study was to evaluate the efficacy of mononuclear cells from human umbilical cord blood in promoting functional recovery when transplanted after a contusion spinal cord injury. Female Wistar rats (12 weeks old) were submitted to spinal injury with a MASC
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-01
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9. O uso de células-tronco adultas humanas na recuperação funcional da lesão medular trumática em ratas Wistar
Spinal cord injury is a debilitating disease and yet no effective treatment is available. In this framework cell therapy represents a new strategy to treat this condition. Adult stem cells are potential sources for cell transplantation in order to minimize injury and promote the recovery of damaged tissues, such as the spinal cord. The purpose of this Thesis
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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10. Comparative quantification of umbilical cord blood CD34+ and CD34+ bright cells using the procount tm-bd and ishage protocols
The total number of CD34+ cells is the most relevant clinical parameter when selecting human umbilical cord blood (HUCB) for transplantation. The objective of the present study was to compare the two most commonly used CD34+ cell quantification methods (ISHAGE protocol and ProCount™ - BD) and analyze the CD34+ bright cells whose 7-amino actinomycin D (7AAD
Publicado em: 2010
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11. Establishment of an adherent cell layer from human umbilical cord blood
In addition to bone marrow and peripheral blood, stem cells also occur in human umbilical cord blood (HUCB), and there is an increasing interest in the use of this material as an alternative source for bone marrow transplantation and gene therapy. In vitro hematopoiesis has been maintained for up to 16 weeks in HUCB cultures, but the establishment of an adhe
Publicado em: 2010
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12. Isolamento e caracterização de células-tronco caninas do cordão umbilical para uso potencial em transplantes de cães distróficos / Isolation and characterization of canine umbilical cord stem cells for potential use in transplantation of dystrophic dogs
A Distrofia Muscular de Duchenne (DMD) é a forma mais comum e grave de Distrofia Muscular Progressiva. Esta doença possui herança recessiva ligada ao X e é caracterizada pela ausência de distrofina na membrana das fibras musculares. A DMD afeta 1/3.000 meninos nascidos vivos, e até os 12 anos de idade os pacientes são confinados à cadeira de rodas. O
Publicado em: 2009