Uremic Toxins
Mostrando 1-12 de 50 artigos, teses e dissertações.
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1. Uremic neuropathy: an overview of the current literature
RESUMO INTRODUÇÃO: A neuropatia periférica (NU) é um distúrbio que afeta o corpo celular, o axônio ou a mielina do motor ou neurônios sensoriais periféricos e ocorre em 60%-100% dos pacientes que são submetidos à diálise por doença renal crônica. A neuropatia urêmica é atribuída à acumulação de resíduos orgânicos, evidente em pacientes
Rev. Assoc. Med. Bras.. Publicado em: 11/04/2019
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2. Uremic neuropathy: an overview of the current literature
RESUMO INTRODUÇÃO: A neuropatia periférica (NU) é um distúrbio que afeta o corpo celular, o axônio ou a mielina do motor ou neurônios sensoriais periféricos e ocorre em 60%-100% dos pacientes que são submetidos à diálise por doença renal crônica. A neuropatia urêmica é atribuída à acumulação de resíduos orgânicos, evidente em pacientes
Rev. Assoc. Med. Bras.. Publicado em: 2019-02
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3. Detection of E. coli O157:H7 and Shigella dysenteriae toxins in clinical samples by PCR-ELISA
Shiga toxin producing bacteria are potential causes of serious human disease such as hemorrhagic colitis, severe inflammations of ileocolonic regions of gastrointestinal tract, thrombocytopenia, septicemia, malignant disorders in urinary ducts, hemolytic uremic syndrome (HUS) Shiga toxin 1 (stx1), shiga toxin 2 (stx2), or a combination of both are responsibl
Braz J Infect Dis. Publicado em: 2015-06
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4. Efeito das toxinas urêmicas p-cresol e espermidina sobre o mecanismo de apoptose e função de neutrófilos polimorfonucleares (PMN). / Effects of spermidine and p-cresol on polymorphonuclear cell apoptosis and function.
Introdução: As infecções são a segunda causa de mortalidade e a primeira causa de morbidade em pacientes com doença renal crônica (DRC). Neutrófilos Polimorfonucleares (PMN) de pacientes com DRC apresentam várias alterações funcionais, que incluem menor capacidade na produção de espéceis reativas de oxigênio (ERO), migração celular, além de
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/03/2009
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5. Anticorpos anti-Stx como ferramentas na detecção de Escherichia coli produtora da toxina de Shiga (STEC). / Antibodies anti-Stx as tools on detection of Shiga toxin-producing Escherichia coli (STEC).
STEC infection is a public health problem, causing hemolytic-uremic syndrome and haemorrhagic colitis. The detection of STEC isolates depends on a sensitive, specific and low cost diagnostic method. Thus, the aim of this study was to develop a capture ELISA using polyclonal and monoclonal antibodies. For this purpose, first of all a growth media that induce
Publicado em: 2008
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6. Epithelial cell signaling responses to enterohemorrhagic Escherichia coli infection
Enterohemorrhagic Escherichia coli, including the serotype O157:H7 that is most commonly identified with human disease, cause both sporadic cases and outbreaks of non-bloody diarrhea and hemorrhagic colitis. In about 10% of infected subjects, the hemolytic uremic syndrome (hemolytic anemic, thrombocytopenia, and acute renal failure) develops, likely as a con
Memórias do Instituto Oswaldo Cruz. Publicado em: 2005-03
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7. Inhibition of calcitriol receptor binding to vitamin D response elements by uremic toxins.
The genomic action of calcitriol (1,25-dihydroxy-vitamin D3) is mediated through the interaction of the calcitriol receptor (VDR) with vitamin D response elements (VDREs). Although renal failure is associated with resistance to the action of calcitriol, the mechanism of this resistance is not well understood. Therefore, we used the electrophoretic mobility s
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8. Shiga toxin-associated hemolytic uremic syndrome: effect of sodium butyrate on sensitivity of human umbilical vein endothelial cells to Shiga toxin.
Escherichia coli O157:H7-related vascular damage such as hemolytic uremic syndrome is believed to require the Shiga-like toxins. This study demonstrated that sodium butyrate sensitized human umbilical vein endothelial cells to Shiga toxin and increased the expression of Shiga toxin receptor, globotriaosylceramide (Gb3), on human umbilical vein endothelial ce
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9. Antibody Therapy in the Management of Shiga Toxin-Induced Hemolytic Uremic Syndrome
Hemolytic uremic syndrome (HUS) is a disease that can lead to acute renal failure and often to other serious sequelae, including death. The majority of cases are attributed to infections with Escherichia coli, serotype O157:H7 strains in particular, which cause bloody diarrhea and liberate one or two toxins known as Shiga toxins 1 and 2. These toxins are tho
American Society for Microbiology.
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10. Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities.
Escherichia coli O157:H7 strain 933 contains two distinct toxin-converting phages (933J and 933W). The biologic activities and antigenic relationship between the toxins produced by 933J and 933W lysogens of E. coli K-12, as well as the homology of the genes that encode the two toxins, were examined in this study. The 933J and 933W toxins, like Shiga toxin pr
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11. Sorbitol-negative phenotype among enterohemorrhagic Escherichia coli strains of different serotypes and from different sources.
Enterohemorrhagic Escherichia coli (EHEC) strains detected with DNA probes (for virulence plasmid and Shiga-like toxins) from subjects with hemolytic-uremic syndrome (n = 19) or diarrhea (n = 41) or asymptomatic carriers (n = 29) were examined for sorbitol fermentability, as were enterotoxigenic (n = 40), enteropathogenic (n = 40), and enteroinvasive (n = 40
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12. Urea inhibits NaK2Cl cotransport in human erythrocytes.
We examined the effect of urea on NaK2Cl cotransport in human erythrocytes. In erythrocytes from nine normal subjects, the addition of 45 mM urea, a concentration commonly encountered in uremic subjects, inhibited NaK2Cl cotransport by 33 +/- 7%. Urea inhibited NaK2Cl cotransport reversibly, and in a concentration-dependent fashion with half-maximal inhibiti