A case of progressive spinocerebellar syndrome due to isolated vitamin E deficiency is reported. Measurement of the vitamin E concentration in serum should be included when investigating all children with unexplained, progressive ataxia, even in the absence of malabsorption. Repl...
Ver documentoABSTRACT Purpose: Overactive bladder (OAB) is a common syndrome associated with lower urinary tract symptoms (LUTS), especially urinary incontinence in children, which may affect the patient's quality of life (QoL). Vitamin D deficiency has been shown to be associated with OAB s...
Ver documentoThree patients are described, and they provide further evidence that deficiency of folic acid and vitamin B12 may sometimes affect small intestinal function. Malabsorption of both xylose and vitamin B12 returned to normal in one patient after treatment of a megaloblastic anaemia ...
Ver documentoAbstract Objective To evaluate the prevalence of vitamin D deficiency in obese children and adolescents when compared to eutrophic controls. Methods Systematic review with meta-analysis covering studies with patients aged 0–18 years old diagnosed with obesity and vitamin D defi...
Ver documentoA patient with multiple injuries developed a severe coagulation defect due to a deficiency of vitamin K. None of the usual predisposing factors was present and the patient's diet was very poor. Dietary deficiency of vitamin K and the importance of antibiotic therapy in its produc...
Ver documentoVitamin D deficiency is increasingly being recognized as a prevalent problem in the general population. Patients with chronic lung diseases such as asthma, cystic fibrosis, chronic obstructive lung disease and interstitial pneumonia appear to be at increased risk for vitamin D de...
Ver documentoRats were raised after weaning on a vitamin D-deficient diet which used whole wheat and casein as the major protein source. For at least the first year of life, plasma calcium concentrations of these rats were the same as those of vitamin D-replete rats, and the rate of growth wa...
Ver documentoWe studied the effects of vitamin A deficiency and repletion on rat insulin release and islet cellular retinol binding protein (CRBP) and cellular retinoic acid binding protein (CRABP). Biphasic insulin release from vitamin A-deficient perifused islets was markedly impaired. Rele...
Ver documentoABSTRACT The effects of vitamin D on the musculoskeletal system are well established. Its deficiency causes osteomalacia, secondary hyperparathyroidism, and an increased risk for fractures and falls. However, clinical and experimental evidence points to extra-skeletal actions of ...
Ver documentoVitamin A deficiency has been considered a nutritional problem of a moderate to severe level that affects specially children at preschool age. Furthermore, it has also been considered that this deficiency affect children at school age. The present study, using a transversal desig...
Ver documentoWe describe a patient with cystic fibrosis and hepatic involvement who, although on pancreatic extract, developed vitamin A deficiency, night blindness, and a characteristic fundus picture. All of these abnormalities were reversed by oral vitamin A supplementation....
Ver documentoLow vitamin B-12 levels can occur without deficiency being present, and normal levels don't always rule out vitamin B-12 deficiency. A clinical assessment, together with blood count and blood film results, can ensure a correct interpretation of vitamin B-12 and folate levels...
Ver documentoWhen bone is remodeled during the growth of a given size bone to a larger size, some bone is resorbed and some is deposited. Much of the resorbed bone mineral, calcium, can be reutilized during bone formation. The net and absolute effects of normal growth, vitamin D deficiency, o...
Ver documentoFolic acid deficiency with the picture of a megaloblastic bone marrow may develop in haemolytic anaemia, and, on the other hand, both vitamin B12 and folic acid deficiency may produce signs of haemolysis. As the correct interpretation of a positive antiglobulin reaction associate...
Ver documentoABSTRACT Studies on B-vitamin requirements of cattle, conducted more than 60 years ago, concluded that mature ruminants do not require B-vitamin supplements because the amounts of vitamins provided by the diet and synthesized by the ruminal microflora were sufficient to prevent e...
Ver documentoAbstract Introduction There have been reports indicating that patients with frequently recurring benign paroxysmal positional vertigo (BPPV) had vitamin D deficiency, and some studies indicated that the treatment of severe vitamin D deficiency is effective in the reduction of th...
Ver documentoThirty six patients with rheumatoid arthritis (RA) (25 with anaemia) were studied to establish the role of iron, vitamin B12, and folic acid deficiency, erythropoietin responsiveness, and iron absorption in the diagnosis and pathogenesis of anaemia in RA. Iron deficiency, assesse...
Ver documento1. Mesenteric arterial beds from male rats deprived of vitamin E for 12 months postweaning were isolated and perfused at 5 ml min-1. 2. The basal perfusion pressure of vitamin E-deficient preparations was significantly higher (34.0 +/- 1.9 mmHg, n = 15) than in age-matched contro...
Ver documentoAbstract Introduction Benign paroxysmal positional vertigo (BPPV) appears during the same age group in which vitamin D and calcium deficiencies are evident. Vitamin D deficiency could predispose to BPPV, since these two entities share a demineralization process. Objective To est...
Ver documentoAlthough lipid peroxidation in the subendothelial space has been hypothesized to play a central role in atherogenesis, the role of vitamin E in preventing lipid peroxidation and lesion development remains uncertain. Here we show that in atherosclerosis-susceptible apolipoprot...
Ver documentoAlthough low plasma vitamin A levels are associated with increased mortality and higher vertical transmission during human immunodeficiency virus (HIV) infection, it is unknown whether plasma low vitamin A levels are a marker for circulating HIV load. We conducted a cross-section...
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