Zimosan Farmacologia
Mostrando 1-6 de 6 artigos, teses e dissertações.
-
1. Estudo Comparativo entre os Enantiômeros da Carvona em Modelos de Inflamação Aguda e de Hipersensibilidade Imediata
Enantiômeros são compostos assimétricos que apresentam a particularidade de serem imagens especulares um do outro, não sobreponíveis e por terem comportamentos diferentes em ambientes quirais, resultando frequentemente na discriminação esterioseletiva e diferentes efeitos biológicos. A carvona é um monoterpeno, constituinte de muitos óleos essencia
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2011
-
2. Estudo do efeito da fraÃÃo nÃo dialisÃvel do lÃtex de Calotropis procera (ait) R. Br em modelos experimentais de inflamaÃÃo, com Ãnfase em artrite / Study of the effect of the non-dialyzable fraction of Calotropis procera (Ait) R. Br latex in experimental models of inflammation, with emphasis in arthritis
The objective of this dissertation was to investigate the effect of the latex from Calotropis procera in experimental models of inflammation, with special focus on arthritis. The plant belongs to Asclepiadaceae family and is largely found in Northeast of Brazil. The plant latex presents clear anti-inflammatory effects, which is kept by its non-dialyzable pro
Publicado em: 2007
-
3. Participação do óxido nítrico (NO) na modulação central da hiperalgesia na artrite induzida por zymozan (AZy) em ratos. / Nitric oxide (NO) participation in central hyperralgesia modulation in modulation in the zymozan induced artritis (AZy) in rats.
We investigate in this work the role of the central nervous system in the modulation of the inflammatory peripheral pain in the zymosan induced arthritis (AZy) in rats. Cerebrospinal fluid (CSF) and sinovial fluid were collected from animals at different AZy times (1, 3, 6, 12 and 14 hours) in order to determine the nitrite level. Different groups of male, W
Publicado em: 2006
-
4. Study of participation of nitric oxide about acute cellular migration in the arthritis and peritonitis induced by zymosan or lipopolysaccharide in experimental models / Estudo da participação do óxido nítrico na migração celular aguda na artrite e peritonite induzidas por zymosan ou lipopolissacarídeo em modelos experimentais
Cell influx (CI) to synovium participates in physiopathology of rheumatoid arthritis (RA). There are controversies about the nitric oxide (NO) action in modulation of neutrophil influx to inflammatory sites, with NO decreasing or increasing it. This study investigated the effect of nitric oxide synthase (NOS) inhibitors on acute CI in animals submitted to ar
Publicado em: 2005
-
5. Potential effect of the antineoplasic Paclitaxel (Taxol) in the experimental inflammatory hyperalgisia induced by zymosan. / Efeito potencializador do antineoplásico paclitaxel (taxol) na hiperalgesia inflamatória experimental induzida por zymosan.
Paclitaxel (Taxol) was the first effective antineoplastic in the management of refractory neoplasias to the conventional chemotherapy. It induces clinically to myelosuppression and sensory peripheral neuropathy boundary and cumulative dose, well documented at literature already. Less often the patients exhibited myalgias and arthralgias. As to concern to the
Publicado em: 2003
-
6. Atividade analgesica das interleucinas 4, 10 e 13 (IL-4, IL-10 e il-13) na dor inflamatoria experimental : papel de celulas residentes e citocinas / Analgesic activity of interleukines 4, 13 and 10 (IL-4, IL-13 and IL-10) in experimental inflammatory pain: role of resident cells and cytokines
The release of cyclo-oxigenase products and sympathomimetics amines, the final mediators of inflammatory pain, is preceded by the generation of cytokines by resident cells. In recent years a number of cytokines such as IL-4, IL-10, IL-13, IL-6, TGF-β e IFN-α have been described to inhibit the production of TNF-α, IL-1β, IL-6 and IL-8 (cyt
Publicado em: 2000